1003048-72-3 | 4-broMo-7-fluoro-2,3-dihydroinden-1-one

CAS:1003048-72-3 | 4-broMo-7-fluoro-2,3-dihydroinden-1-one,Description

“4-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one” is a chemical compound with the CAS Number: 1003048-72-3. It has a molecular weight of 229.05and its linear formula is C9H6BrFO.

Molecular Structure Analysis

The molecular structure of “4-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one” is represented by the linear formula C9H6BrFO. More detailed structural information, such as 3D conformers, can be found in databases like PubChem.

Physical And Chemical Properties Analysis

“4-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one” is a solid at room temperature. More detailed physicochemical properties, such as LogP, hydrogen bond donor and acceptor count, and topological polar surface area, can be found in databases like PubChem.

Scientific Research Applications

Synthesis of Biologically Active Compounds

Bromo-fluoro-indenone derivatives serve as key intermediates in the synthesis of a wide range of biologically active compounds. For instance, the synthesis of "1-(4-bromo-2-fluorophenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one" demonstrates the utility of similar bromo-fluoro compounds in constructing complex molecules with potential biological activities. This process involves multiple steps, including nitration, chlorination, N-alkylation, reduction, and condensation, showcasing the compound's role in medicinal chemistry for developing new therapeutic agents (Wang et al., 2016).

Materials Science and Nanotechnology

In materials science, bromo-fluoro derivatives are utilized in the synthesis of advanced materials. For example, the development of enhanced brightness, emission-tuned nanoparticles from heterodifunctional polyfluorene building blocks illustrates how such compounds can be instrumental in creating materials with specific optical properties. These materials find applications in optoelectronics, including light-emitting diodes (LEDs) and photovoltaic cells, highlighting the versatility of bromo-fluoro-indenone derivatives in materials engineering (Fischer et al., 2013).

Organic Synthesis and Chemical Reactions

Bromo-fluoro-indenone derivatives are valuable in organic synthesis, serving as precursors or intermediates in various chemical reactions. Their utility in constructing complex molecular architectures is evidenced by their role in generating enantioselective compounds and facilitating novel organic transformations. This application is crucial for synthesizing molecules with precise stereochemical configurations, important in drug development and synthetic chemistry (Schreiner et al., 2002).

Safety And Hazards

The compound has been classified with the signal word “Warning” and is associated with the following hazard statements: H302-H315-H319-H335. This indicates that it may be harmful if swallowed, may cause skin and eye irritation, and may cause respiratory irritation.

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