105529-58-6 | 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene

CAS:105529-58-6 | 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene ,Description

4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene (4-BFMTB) is a chemical compound with a wide range of applications in scientific research and industry. This compound is a halogenated aromatic, which is a type of molecule containing a halogen atom and an aromatic ring. It is known for its excellent solubility in organic solvents, as well as its high reactivity and stability. In addition, 4-BFMTB has been used in a variety of laboratory experiments, including synthesis, chromatography, and spectroscopy. 
 

Scientific Research Applications

• Coordination Chemistry: It's used in the coordination chemistry of fluorocarbons like F(2)-phane and HF-phane to produce complexes with alkali and alkaline earth metal ions (Plenio, Hermann, & Diodone, 1997).
• Synthesis of Triazoles: This chemical is utilized in the synthesis of 1-alkyl-3-fluoro-1H-[1,2,4]triazoles (Zumbrunn, 1998).
• Radiosynthesis: It plays a role in the radiosynthesis of 1-[18F]fluoromethyl-4-methyl-benzene and its derivatives, highlighting its use in radiopharmaceuticals (Namolingam, Luthra, Brady, & Pike, 2001) .
• Organometallic Synthesis: It serves as a starting material for organometallic synthesis, enabling various synthetically useful reactions (Porwisiak & Schlosser, 1996).
• Asymmetric Induction Emission: It exhibits asymmetric induction emission (AIE) peculiarity and shows high fluorescence intensity in both solution and solid state (Zuo-qi, 2015).
• Intermediate in Synthesis: It acts as a key intermediate in synthesizing new organofluorine compounds (Castagnetti & Schlosser, 2001) .
• Environmental Chemistry: An environmentally friendly practical method has been developed for synthesizing 4-Amino-2-(trifluoromethyl)benzonitrile, an intermediate for the synthesis of bicalutamide, showcasing its relevance in green chemistry (Tong-bin, 2012).
• Vibrational and Electronic Absorption Spectroscopy: Its structure and conformational properties have been investigated using spectroscopic techniques, contributing to a deeper understanding of its molecular characteristics (Shishkov, Khristenko, Vilkov, & Oberhammer, 2004).

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