107263-95-6 | 1-Fluoropyridinium triflate

CAS:107263-95-6 | 1-Fluoropyridinium triflate ,Description

1-Fluoropyridinium triflate (1-FPT) is a chemical compound that has been used in a variety of scientific research applications. It is a fluorinated organic compound and a member of the pyridinium family. 1-FPT is a colorless, hygroscopic solid and is soluble in organic solvents such as ethanol and acetonitrile. It has a wide range of applications in the areas of organic synthesis and medicinal chemistry.
 

Scientific Research Applications

• It serves as an effective electrophilic fluorinating agent for preparing sodium trifluoromethanesulfonate and its derivatives (Umemoto, Tomita, & Kawada, 2003) .
• N-Fluoropyridinium triflates are used for the α-fluorination of sulfides under mild conditions, facilitating the easy preparation of α-fluoro sulfoxides or sulfones (Umemoto & Tomizawa, 1986) .
• A stable, bench-stable pyridinium salt including 1-fluoropyridinium triflate can efficiently convert alcohols into benzyl ethers (Poon & Dudley, 2006).
• The compound facilitates a novel three-component reaction to yield imidazo[1,2-a]pyridines, showcasing its utility in organic synthesis (Kiselyov, 2005).
• N,N‘-Difluorobipyridinium salts, related to 1-fluoropyridinium triflate, are used as electrophilic fluorinating agents with high effective fluorine content, suitable for various applications in organic synthesis and catalysis (Umemoto, Nagayoshi, Adachi, & Tomizawa, 1998).
• N-Fluoropyridinium salts react with stabilized sulfur, oxygen, and nitrogen nucleophiles to efficiently produce 2-substituted pyridines (Kiselyov & Strekowski, 1993).
• 18F-labelled N-fluoropyridinium triflate is a new fluorine-18 transfer reagent, demonstrating its potential in radiochemistry (Oberdorfer, Hofmann, & Maier-borst, 1988) .
• The compound has been instrumental in developing a wide range of fluorination reagents, advancing fluorine chemistry and leading to new discoveries and applications in electronic materials (Umemoto, 2014).
• It plays a key role in organoselenium-catalyzed synthesis of oxygen- and nitrogen-containing heterocycles (Guo, Huang, Huang, & Zhao, 2016).

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