1075753-27-3 | 1H-BenziMidazole, 2-chloro-7-(trifluoroMethyl)-

CAS:1075753-27-3 | 1H-BenziMidazole, 2-chloro-7-(trifluoroMethyl)-,Description

2-Chloro-7-(trifluoromethyl)-1H-benzo[d]imidazole is a chemical compound with the CAS Number: 1075753-27-3. It has a molecular weight of 220.58and its IUPAC name is 2-chloro-7-(trifluoromethyl)-1H-benzo[d]imidazole. The compound is solid in physical form.

Molecular Structure Analysis

The InChI code for 2-Chloro-7-(trifluoromethyl)-1H-benzo[d]imidazole is 1S/C8H4ClF3N2/c9-7-13-5-3-1-2-4(6(5)14-7)8(10,11)12/h1-3H,(H,13,14). This indicates the molecular structure of the compound.

Physical And Chemical Properties Analysis

2-Chloro-7-(trifluoromethyl)-1H-benzo[d]imidazole is a solid compound. It should be stored in an inert atmosphere, under -20C.

Scientific Research Applications

• Pharmaceuticals

  • Trifluoromethyl group-containing drugs have been approved by the FDA. The trifluoromethyl (TFM, -CF3) group is a common feature in many of these drugs.
  • The outcomes of these drugs vary widely, as they are used in the treatment of various diseases and disorders.

• Agrochemicals

  • Trifluoromethylpyridines (TFMP) and its derivatives, which also contain the trifluoromethyl group, are used in the agrochemical industry.
  • These compounds are used for the protection of crops from pests. Fluazifop-butyl was the first TFMP derivative introduced to the agrochemical market.
  • The outcomes of these agrochemicals are generally effective pest control, leading to healthier crops and increased yields.

• Material Science

  • Imidazole-based ligands and N-heterocyclic carbenes have shown remarkable catalytic effects on many organic reactions.
  • Fluoroalkyl-derivatized imidazolium-based ionic liquids are becoming increasingly important in the material science area.
  • These ionic liquids are useful in biphasic reaction catalysis, conductive membranes, dye-sensitized solar cells, atom transfer radical polymerization, and as water purification agents.
  • Furthermore, 2-trifluoromethyl-4,5-dicyanoimidazole lithium salt (LiTDI) shows promising results in rechargeable lithium battery technology.

• Pharmaceuticals

  • Imidazoles and benzimidazoles are privileged scaffolds that are present in many biologically active molecules, natural products, pharmaceuticals, and agrochemicals.
  • The imidazole-containing essential amino acid histidine is the precursor of histamine. Histidine and histamine play critical roles in many physiological functions.
  • Anti-histamine drugs (H1-receptor antagonists or inverse agonists) are popular allergy medications.
  • Purines (adenine, guanine), xanthine, theophylline, caffeine, carnosine, and N-acetylcarnosine (NAC) have the imidazole nucleus in their skeletons.

• Green Solvents

  • Fluoroalkyl-derivatized imidazolium-based ionic liquids are becoming increasingly important in the material science area.
  • Besides relative thermal stability and potential use as green solvents, imidazolium ionic liquids are also useful in biphasic reaction catalysis, conductive membranes, dye-sensitized solar cells, atom transfer radical polymerization, and as water purification agents.

• Rechargeable Lithium Battery Technology

  • Furthermore, 2-trifluoromethyl-4,5-dicyanoimidazole lithium salt (LiTDI) shows promising results in rechargeable lithium battery technology.

Safety And Hazards

The compound has been classified under the GHS07 hazard class. The hazard statements associated with it are H302-H315-H319-H335. This means that it can cause skin irritation, serious eye irritation, and may be harmful if swallowed.

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