1193389-14-8 | 4-(trifluoromethyl)piperidin-4-ol hydrochloride

CAS:1193389-14-8 | 4-(trifluoromethyl)piperidin-4-ol hydrochloride,Description

4-(Trifluoromethyl)piperidin-4-ol hydrochloride is a chemical compound with the molecular formula C6H11ClF3NO. It is used in research and development.

Molecular Structure Analysis

The molecular structure of 4-(Trifluoromethyl)piperidin-4-ol hydrochloride consists of a piperidine ring with a trifluoromethyl group and a hydroxyl group attached to the same carbon. The InChI code for this compound is 1S/C6H10F3NO.ClH/c7-6(8,9)5(11)1-3-10-4-2-5;/h10-11H,1-4H2;1H.

Physical And Chemical Properties Analysis

4-(Trifluoromethyl)piperidin-4-ol hydrochloride has a molecular weight of 205.61. It is a solid at room temperature. The compound is stored in an inert atmosphere at room temperature.

Scientific Research Applications

Crystal and Molecular Structure Analysis

• Crystal Structure of Piperidine Derivatives : The crystal and molecular structure of related piperidine compounds, like 4-piperidinecarboxylic acid hydrochloride, has been characterized using X-ray diffraction, computational calculations, and FTIR spectrum, indicating potential applications in structural chemistry and materials science (Szafran, Komasa, & Bartoszak-Adamska, 2007).

Synthesis and Chemical Transformations

• Ultrasound-Promoted Synthesis : Novel bipodal and tripodalpiperidin-4-ones, related to 4-(Trifluoromethyl)piperidin-4-ol hydrochloride, have been synthesized using ultrasound-promoted methods, demonstrating advances in organic synthesis techniques (Rajesh, Reddy, & Vijayakumar, 2012).
• Enantioselective Synthesis : Research includes the enantioselective synthesis of trifluoromethyl substituted piperidines, highlighting applications in asymmetric synthesis and pharmaceutical chemistry (Chen et al., 2015).

Biological and Pharmacological Research

• Anti-tuberculosis Activity : Piperidinol analogs, including compounds similar to 4-(Trifluoromethyl)piperidin-4-ol hydrochloride, have shown interesting anti-tuberculosis activity, suggesting potential pharmaceutical applications (Sun et al., 2009).
• Antimicrobial Activity : Derivatives of piperidin-4-ols, which are structurally related to the compound of interest, have been studied for their antimicrobial activities, indicating their potential in developing new antimicrobial agents (Dyusebaeva, Elibaeva, & Kalugin, 2017).

Novel Synthetic Approaches

• Synthetic Methods Development : Research efforts include developing convenient synthetic approaches for the preparation of various piperidine derivatives, showcasing advancements in organic synthesis and medicinal chemistry applications (Logvinenko, Dolovanyuk, & Kondratov, 2021) .

Miscellaneous Applications

• Growth-Promoting Activity : Certain piperidin-4-ols, related to 4-(Trifluoromethyl)piperidin-4-ol hydrochloride, have demonstrated growth-promoting activities in agricultural contexts, indicating possible applications in agrichemicals (Omirzak et al., 2013).

Safety And Hazards

The safety information for 4-(Trifluoromethyl)piperidin-4-ol hydrochloride indicates that it may be harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Precautionary measures include avoiding breathing dust/fume/gas/mist/vapors/spray and washing thoroughly after handling.

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