120120-26-5 | Triethyl(trifluoromethyl)silane

CAS:120120-26-5 | Triethyl(trifluoromethyl)silane ,Description

Triethyl(trifluoromethyl)silane (TETS) is a colorless, volatile, and highly flammable liquid. It is a member of the trialkylsilane family and is composed of a trifluoromethyl group and three ethyl groups attached to a silicon atom. TETS is used in a variety of applications, including its use as a reagent in organic synthesis, as a fuel additive, and as a precursor for the synthesis of other organosilicon compounds. It is also used in the production of semiconductors, pharmaceuticals, and other materials.
 

Scientific Research Applications

• Regiochemical Course of Metalation: Triethyl[(2-trifluoromethyl)phenyl]silane reacts exclusively at specific positions during metalation, influenced by buttressing effects. This study contributes to understanding the behavior of trifluoromethyl-substituted phenylsilanes in reactions with metalating agents (Schlosser, Heiss, & Leroux, 2006).
• Radical-based Reducing Agent: Tris(trimethylsilyl)silane, a compound similar to Triethyl(trifluoromethyl)silane, serves as an effective reducing agent for various organic compounds. This functionality is vital for synthesizing a wide range of organic substrates (Ballestri et al., 1991).
• Applications in Organic Chemistry: Tris(trimethylsilyl)silane is utilized in radical reductions, hydrosilylation, and consecutive radical reactions, highlighting its versatility in organic chemistry. Its use allows reactions under mild conditions with high yields and selectivity (Chatgilialoglu & Lalevée, 2012).
• Biomedical Applications: A trifluoroethylester-terminal poly(ethylene glycol) silane, related to Triethyl(trifluoromethyl)silane, has been developed for use in biomedical applications like magnetic resonance imaging and controlled drug delivery (Kohler, Fryxell, & Zhang, 2004).
• Advances in Synthetic Chemistry: The use of tris(trimethylsilyl)silane in organic chemistry has evolved over 30 years, showing its significant role in various chemical processes and synthetic strategies (Chatgilialoglu, Ferreri, Landais, & Timokhin, 2018).
• Formation of Inorganic-Organic Layered Materials: Triethoxy(alkyl)silanes, similar in structure to Triethyl(trifluoromethyl)silane, have been used to form organized inorganic–organic layered materials (Shimojima, Sugahara, & Kuroda, 1997).

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