Cart (0)
No products in the cart.
Purchase CAS:1206978-15-5 | 2-chloro-4-(difluoroMethoxy)pyridine,view related peer-reviewed papers,technical documents,similar products,MSDS & more.2-Chloro-4-(difluoromethoxy)pyridine is a chemical compound with the molecular formula C6H4ClF2NO. It has a molecular weight of 179.55 . It is stored under an inert atmosphere at 2-8°C . It is a liquid in its physical form ....
2-Chloro-4-(difluoromethoxy)pyridine is a chemical compound with the molecular formula C6H4ClF2NO. It has a molecular weight of 179.55. It is stored under an inert atmosphere at 2-8°C. It is a liquid in its physical form.
The synthesis of trifluoromethylpyridines, which are structurally similar to 2-Chloro-4-(difluoromethoxy)pyridine, has been discussed in various studies. For instance, 2-chloro-5-(trifluoromethyl)pyridine (2,5-CTF), a key intermediate for the synthesis of fluazifop, can be obtained in good yield via a simple one-step reaction.
The InChI code for 2-Chloro-4-(difluoromethoxy)pyridine is 1S/C6H4ClF2NO/c7-5-3-4(1-2-10-5)11-6(8)9/h1-3,6H. The InChI key is NPMVJHJZXXNKCH-UHFFFAOYSA-N.
2-Chloro-4-(difluoromethoxy)pyridine is a liquid in its physical form. It is stored under an inert atmosphere at 2-8°C. The unique physicochemical properties of the fluorine atom and the unique characteristics of the pyridine moiety contribute to its biological activities.
Trifluoromethylpyridine (TFMP) derivatives, which include “2-Chloro-4-(difluoromethoxy)pyridine”, are widely used in the agrochemical and pharmaceutical industries. The major use of TFMP derivatives is in the protection of crops from pests. Several TFMP derivatives are also used in the pharmaceutical and veterinary industries.
The biological activities of TFMP derivatives are thought to be due to the combination of the unique physicochemical properties of the fluorine atom and the unique characteristics of the pyridine moiety. More than 20 new TFMP-containing agrochemicals have acquired ISO common names. Additionally, five pharmaceutical and two veterinary products containing the TFMP moiety have been granted market approval, and many candidates are currently undergoing clinical trials.
“2-Chloro-4-(difluoromethoxy)pyridine” is used as an intermediate in the synthesis of various fluorinated pyridines. Fluorinated pyridines have interesting and unusual physical, chemical, and biological properties owing to the presence of the strong electron-withdrawing substituent(s) in the aromatic ring. They have reduced basicity and are usually less reactive than their chlorinated and brominated analogues.
Fluoropyridines have found applications in various fields due to their unique properties. In the search for new agricultural products having improved physical, biological, and environmental properties, one of the most generally useful chemical modifications is the introduction of fluorine atoms into lead structures. About 10% of the total sales of pharmaceuticals currently used for medical treatment are drugs containing a fluorine atom.
“2-Chloro-4-(difluoromethoxy)pyridine” is used as an intermediate in the synthesis of various fluorinated pyridines. Fluorinated pyridines have interesting and unusual physical, chemical, and biological properties owing to the presence of the strong electron-withdrawing substituent(s) in the aromatic ring. They have reduced basicity and are usually less reactive than their chlorinated and brominated analogues.
Fluoropyridines have found applications in various fields due to their unique properties. In the search for new agricultural products having improved physical, biological, and environmental properties, one of the most generally useful chemical modifications is the introduction of fluorine atoms into lead structures. About 10% of the total sales of pharmaceuticals currently used for medical treatment are drugs containing a fluorine atom.
2-Chloro-4-(difluoromethoxy)pyridine is considered hazardous. It is recommended to avoid all personal contact, including inhalation. Protective clothing should be worn when there is a risk of exposure. It should be used in a well-ventilated area and contact with moisture should be avoided.
Product Name: | 2-chloro-4-(difluoroMethoxy)pyridine |
Synonyms: | 2-chloro-4-(difluoroMethoxy)pyridine;Pyridine, 2-chloro-4-(difluoromethoxy)- |
CAS: | 1206978-15-5 |
MF: | C6H4ClF2NO |
MW: | 179.55 |
EINECS: | |
Product Categories: | |
Mol File: | 1206978-15-5.mol |
2-chloro-4-(difluoroMethoxy)pyridine Chemical Properties |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
form | liquid |
color | Clear, faint yellow |