Purchase CAS:1211591-93-3 | 6-BroMo-2-chloro-3-fluoropyridine,view related peer-reviewed papers,technical documents,similar products,MSDS & more.6-Bromo-2-chloro-3-fluoropyridine is a chemical compound with the CAS Number: 1211591-93-3 . It has a molecular weight of 210.43 and is commonly stored in an inert atmosphere at temperatures between 2-8°C . It is a solid substance and is considered a useful intermediate for pharmaceutical and orga...
6-Bromo-2-chloro-3-fluoropyridine is a chemical compound with the CAS Number: 1211591-93-3. It has a molecular weight of 210.43and is commonly stored in an inert atmosphere at temperatures between 2-8°C. It is a solid substanceand is considered a useful intermediate for pharmaceutical and organic synthesis.
Synthesis Analysis
The synthesis of fluorinated pyridines, such as 6-Bromo-2-chloro-3-fluoropyridine, is a topic of interest due to their unusual physical, chemical, and biological properties. Fluoropyridines have reduced basicity and are usually less reactive than their chlorinated and brominated analogues. A selective synthesis of fluoropyridines remains a challenging problem.
Molecular Structure Analysis
The molecular formula of 6-Bromo-2-chloro-3-fluoropyridine is C5H2BrClFN. The InChI code for this compound is 1S/C5H2BrClFN/c6-4-2-1-3(8)5(7)9-4/h1-2H.
Scientific Research Applications
Scientific Field: Organic Chemistry
Application : Fluoropyridines are used in the synthesis of various organic compounds. They have interesting and unusual physical, chemical, and biological properties due to the presence of strong electron-withdrawing substituents in the aromatic ring.
Methods of Application : The methods of synthesis of 2-, 3-, 4-fluoropyridines, di-, tri-, polyfluoropyridines, perfluoroalkylpyridines and also fluoropyridines fused with carbo-, heterocycles are presented.
Results : Fluoropyridines have reduced basicity and are usually less reactive than their chlorinated and brominated analogues.
Scientific Field: Agrochemical Industry
Application : Fluoropyridines are used in the protection of crops from pests. More than 20 new trifluoromethylpyridine (TFMP)-containing agrochemicals have acquired ISO common names.
Methods of Application : The specific methods of application are not mentioned in the source.
Results : The biological activities of TFMP derivatives are thought to be due to the combination of the unique physicochemical properties of the fluorine atom and the unique characteristics of the pyridine moiety.
Scientific Field: Pharmaceutical Industry
Application : Several trifluoromethylpyridine (TFMP) derivatives are used in the pharmaceutical and veterinary industries.
Methods of Application : The specific methods of application are not mentioned in the source.
Results : Five pharmaceutical and two veterinary products containing the TFMP moiety have been granted market approval, and many candidates are currently undergoing clinical trials.
Scientific Field: Synthesis of Fluorinated Pyridines
Application : Fluoropyridines are used as starting materials for the synthesis of some herbicides and insecticides.
Methods of Application : The methods of synthesis of 2-, 3-, 4-fluoropyridines, di-, tri-, polyfluoropyridines, perfluoroalkylpyridines and also fluoropyridines fused with carbo-, heterocycles are presented.
Results : Examples of synthesis substituted 2,6-difluoropyridines are not numerous.
Scientific Field: Organic Synthesis
Application : 4-Bromo-3-chloro-2-fluoropyridine, a similar compound to 6-Bromo-2-chloro-3-fluoropyridine, is used as an intermediate for pharmaceutical and organic synthesis.
Methods of Application : The specific methods of application are not mentioned in the source.
Results : The results or outcomes obtained are not mentioned in the source.
Scientific Field: Synthesis of F 18 Substituted Pyridines
Application : Methods for synthesis of F 18 substituted pyridines for local radiotherapy of cancer and other biological active compounds are also presented.
Methods of Application : The specific methods of application are not mentioned in the source.
Results : The results or outcomes obtained are not mentioned in the source.
Safety And Hazards
The safety information for 6-Bromo-2-chloro-3-fluoropyridine indicates that it has a GHS07 pictogram and a warning signal word. Hazard statements include H315 and H319. Precautionary statements include P264, P280, P302+P352, P337+P313, P305+P351+P338, P362+P364, and P332+P313.
Future Directions
While specific future directions for 6-Bromo-2-chloro-3-fluoropyridine are not explicitly mentioned in the available literature, the compound’s fluoropyridine structure suggests potential applications in the development of new agricultural products and pharmaceuticals. The introduction of fluorine atoms into lead structures is a common chemical modification used to improve physical, biological, and environmental properties.