1235865-75-4 | Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate

CAS:1235865-75-4 | Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate,Description

“Methyl 2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)-4-fluorobenzoate” is a chemical compound with the molecular formula C19H20N4O3 and a molecular weight of 352.39. It is also known by other names such as “methyl 4-piperazin-1-yl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate” and "Benzoic acid, 4-(1-piperazinyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, methyl ester".

Synthesis Analysis

The synthesis of “Methyl 2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)-4-fluorobenzoate” and its derivatives has been reported in the literature. These compounds have been synthesized as part of a series of 1H-pyrrolo[2,3-b]pyridine derivatives with potent activities against FGFR1, 2, and 3.

Molecular Structure Analysis

The molecular structure of “Methyl 2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)-4-fluorobenzoate” consists of a pyrrolo[2,3-b]pyridine core with a methoxy group attached to the 2-position and a fluorobenzoate group attached to the 4-position.

Scientific Research Applications

Evaluation of Health Aspects and Toxicity

Research on similar compounds, such as methyl paraben, highlights the importance of evaluating health aspects and toxicity for chemical compounds used in foods, drugs, and cosmetics. Methyl paraben, for example, has been extensively studied for its antimicrobial properties, absorption, metabolism, and excretion in humans, indicating its safety for over 50 years of use. Such studies are critical for understanding the potential health impacts of chemical compounds, including methyl 2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)-4-fluorobenzoate, if used in consumer products (Soni, Taylor, Greenberg, & Burdock, 2002).

Chemical Synthesis and Pharmaceutical Impurities

Another relevant area of research involves the synthesis of complex molecules and the study of pharmaceutical impurities. For example, novel synthesis methods for omeprazole and its impurities provide insights into the development of proton pump inhibitors and the control of pharmaceutical impurities. Such research is essential for improving drug synthesis processes and ensuring the quality of pharmaceuticals (Saini, Majee, Chakraborthy, & Salahuddin, 2019).

Chemical Structure Analysis

The evaluation of metal(II) 2-fluorobenzoate complexes highlights the significance of detailed structural analysis in reaching target molecules by understanding factors affecting structure. This type of research contributes to future studies by providing a foundation for designing molecules with desired physical and biological properties (Öztürkkan & Necefoğlu, 2022) .

Environmental and Biological Impacts

Studies on the occurrence, fate, and behavior of parabens in aquatic environments review the knowledge regarding their biodegradability, ubiquity in water bodies, and potential as weak endocrine disruptors. Research in this domain underscores the importance of understanding the environmental and biological impacts of chemical compounds, which is also relevant for assessing the implications of using methyl 2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)-4-fluorobenzoate in various applications (Haman, Dauchy, Rosin, & Munoz, 2015).

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