1269151-38-3 | Ethyl 2,2,2-trifluoroethyl oxalate

CAS:1269151-38-3 | Ethyl 2,2,2-trifluoroethyl oxalate ,Description

Ethyl 2,2,2-trifluoroethyl oxalate (ETFO) is a trifluoroethyl ester of oxalic acid. It is a colorless, odorless, and non-toxic liquid with a boiling point of 98 °C and a melting point of -60 °C. ETFO is used in a variety of applications, such as organic synthesis, pharmaceuticals, and biochemistry. It is also used as a reagent in laboratory experiments due to its stability and low volatility. 
Fluorinated lithium battery additives remain stable under high pressure, with the ability to form films and increase the flash point, thus enhancing safety.

Scientific Research Applications

• High Voltage Electrochemical Capacitors

  • Ethyl 2,2,2-trifluoroethyl oxalate (ETFEC) was studied as a fluorinated additive in electrochemical capacitor electrolytes. This research aimed at improving stability at voltages above 2.7V. ETFEC showed promise in increasing the operating limits of electric double-layer type supercapacitors, suggesting its potential in enhancing energy storage and compatibility with lithium-ion battery cells (Krause et al., 2021).

• Non-Flammable Electrolytes for Lithium-Ion Batteries

  • A study presented a safe electrolyte for lithium-ion batteries containing a mix of lithium difluoro(oxalato)borate, propylene carbonate, and tris(2,2,2-trifluoroethyl)phosphate. This formulation, with its non-flammable characteristics and improved compatibility with graphite anodes, showed potential for practical application in lithium-ion batteries (Gu et al., 2020).

• Electrolytes in Li-ion Batteries with High-Voltage Cathodes

  • Research on ETFEC as a solvent component in high-voltage electrolytes for LiNi0.5Mn1.5O4 cathodes in lithium-ion batteries indicated significant improvement in self-discharge behavior and high-temperature cycle performance. The stability of ETFEC prevents extensive electrolyte oxidation, which is crucial for enhancing the longevity and efficiency of lithium-ion batteries (Zheng et al., 2020).

• Synthesis of Alkylating Agents

  • The alkylating agent 2,2,2-trifluoroethyl triflate, synthesized using ethyl [2-18 F]-trifluoroacetate, was studied for its potential in labeling compounds such as 2-oxoquazepam. This synthesis method is relevant for the production of labeled compounds used in various scientific and medical applications (Johnström & Stone-Elander, 1995) .

• Synthesis of Hindered Aliphatic Oxamides

  • The use of methyl and bis(2,2,2-trifluoroethyl) oxalate in a parallel synthesis approach to create unsymmetrical N1,N2-substituted aliphatic oxamides was explored. This method offered high overall success rates in moderate yields, highlighting its utility in synthesizing complex organic compounds (Bogolubsky et al., 2016) .

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