138495-42-8 | 1,1,1,2,2,3,4,5,5,5-Decafluoropentane

CAS:138495-42-8 | 1,1,1,2,2,3,4,5,5,5-Decafluoropentane ,Description

1,1,1,2,2,3,4,5,5,5-Decafluoropentane (DF) is an organofluorine compound that is used in a variety of scientific and industrial applications. It is a colorless and odorless gas with a boiling point of -54.5°C and a melting point of -106°C. DF is used in a variety of scientific and industrial applications, such as in the production of speciality chemicals, as a propellant in aerosols, and as a solvent for organic compounds. Additionally, DF has been studied for its potential applications in biological research, due to its ability to penetrate cell membranes and interact with biological molecules. In 
 

Scientific Research Applications

In Vitro Cytotoxicity in Perfluorocarbon Liquids

A study compared in vitro cytotoxicity tests using direct contact and tests on liquid extracts of compounds in perfluorocarbon liquids (PFCLs) for vitreoretinal surgery. This research included 1,1,1,2,2,3,4,5,5,5-Decafluoropentane among other compounds and utilized 19F NMR spectroscopy for analysis. The study concluded that direct contact tests are more reliable for detecting possible cytotoxic impurities in PFCLs, ensuring patient safety (Gatto et al., 2022).

Transformation into Functionalized Polyfluorinated Compounds

Research on transforming 2H,3H-decafluoropentane into (Z)-2H-nonafluoropent-2-ene demonstrated its potential as an inexpensive and easy-to-handle chemical feedstock for synthesizing densely functionalized polyfluorinated organic compounds. This process involves nucleophilic substitution reactions and Claisen rearrangement (Agou et al., 2018).

Electrochemical Applications in Non-Aqueous Medium

A study highlighted the applicability of 1,1,1,2,3,4,4,5,5,5-decafluoropentane as a fluorous solvent in non-aqueous medium for liquid-liquid electrochemistry. The research showed the solvent's high conductivity and potential for studying various ion-transfer reactions at interfaces (Katano et al., 2017).

Vapor-Liquid Equilibria in Binary Mixtures

Investigations into the vapor-liquid equilibria of binary mixtures involving 1,1,1,2,3,4,4,5,5,5-decafluoropentane have been conducted. These studies are crucial for understanding the thermodynamic properties of mixtures containing this compound (Kao et al., 2001).

Diffusion in Amorphous Glassy Perfluorodioxole Copolymer

Research on the diffusion of decafluoropentane in amorphous glassy perfluorodioxole copolymer provided insights into the translational motion of penetrant molecules. This study is significant for understanding the behavior of decafluoropentane in various polymeric systems (Wang et al., 2001).

Atmospheric Abundance and Emission Estimates

The atmospheric measurements and global emission estimates of HFC-43-10mee, which includes 1,1,1,2,2,3,4,5,5,5-decafluoropentane, have been reported. This research provides critical data on the environmental impact of this compound (Arnold et al., 2014) .

Ultrasound-Activated Oxygen Delivery

Studies on ultrasound-activated perfluoropentane-cored nanobubbles and nanodroplets, including decafluoropentane, have demonstrated their potential in delivering oxygen to hypoxic tissues. This research is particularly relevant for treating hypoxia-associated pathologies (Magnetto et al., 2014).

Drug-Propellant Interactions in Pressurized Metered Dose Systems

Investigations into the interactions between active pharmaceutical ingredients and model propellants, including 2H,3H-decafluoropentane, have been crucial for developing pressurized metered dose inhalers (pMDIs) (Ooi et al., 2014).

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