14533-84-7 | Pentafluorophenyl trifluoroacetate

CAS:14533-84-7 | Pentafluorophenyl trifluoroacetate ,Description

Pentafluorophenyl trifluoroacetate, also known as PFPTA, is a compound of pentafluorophenyl and trifluoroacetate and is used as a reagent in organic synthesis. It is an important intermediate in the synthesis of pharmaceuticals, agrichemicals, and other organic compounds. It is a colorless, volatile liquid with a boiling point of 101.8°C and a melting point of -46.3°C. PFPTA is also soluble in organic solvents and insoluble in water.
 

Scientific Research Applications

• Catalysis in Polymerization: Tris(pentafluorophenyl)borane is used as a catalyst in homogeneous Ziegler-Natta chemistry for olefin polymerization and other organic and organometallic reactions (Erker, 2005).
• Co-catalyst in Metallocene-based Processes: Pentafluorophenylboranes, including tris(pentafluorophenyl)borane, have significant roles as co-catalysts in metallocene-based industrial processes for olefin polymerization (Piers & Chivers, 1998).
• Hydrosilylation of Amides: Tris(pentafluorophenyl)boron acts as an effective catalyst for the hydrosilylative reduction of tertiary and N-phenyl secondary amides (Chadwick et al., 2014).
• Lewis Acid Catalysis: Tris(pentafluorophenyl)boron is an efficient, air-stable, and water-tolerant Lewis acid catalyst for various chemical reactions, including aldol-type and Michael reactions (Ishihara et al., 1995).
• Borylation Chemistry: Tris(pentafluorophenyl)borane, due to its high Lewis acidity, is widely used in reactions like borylation, hydrogenation, hydrosilylation, and frustrated Lewis pair (FLP) chemistry (Lawson & Melen, 2017).
• Improving Lithium-Ion Battery Power: Tris(pentafluorophenyl) borane was investigated as an electrolyte additive to enhance the power capabilities of lithium-ion batteries (Chen & Amine, 2006).
• Organic Synthesis and Modification: Pentafluorophenylboranes are used in the sulfonation and deuteration of organic compounds like free-base corroles (Gross & Mahammed, 2002).
• Fluorination of Organic Molecules: Pentafluorophenyl moieties are transferred to various fluorinated inorganic and organic sulfur and carbon centers for the preparation of fluorinated molecules (Patel & Kirchmeier, 1992).
• In Polymerization Processes: Tris(pentafluorophenyl)borane is used as a catalyst to lower the ring-opening polymerization temperature of certain organic compounds (Arslan et al., 2018).
• In Solid-Phase Synthesis: Pentafluorophenyl S-acetylmercaptoacetate is used in solid-phase synthesis for the modification of peptides (Drijfhout et al., 1990).
• In Advanced Battery Technologies: Tris (pentafluorophenyl) phosphine is used as an electrolyte additive in high-voltage lithium-ion batteries (Xu et al., 2012).

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