1535-65-5 | ((Difluoromethyl)sulfonyl)benzene

CAS:1535-65-5 | ((Difluoromethyl)sulfonyl)benzene ,Description

((Difluoromethyl)sulfonyl)benzene, commonly abbreviated as DFMSB, is a fluorinated aromatic compound that has recently become popular in the scientific community due to its unique properties and potential applications. DFMSB is an organic compound, containing a benzene ring with two fluorine atoms and a sulfonyl group attached to it. It is a colorless, odorless, and non-toxic compound that is soluble in many organic solvents. DFMSB has attracted attention from scientists due to its potential applications in organic synthesis, medicinal chemistry, and materials science.
 

Scientific Research Applications

• Synthesis of Pharmaceuticals: Benzene sulfonyl compounds, similar to ((Difluoromethyl)sulfonyl)benzene, are used in the selective alkylation of the N-H of pyrrolopyrimidines and 5-aminoindoles, which facilitates the synthesis of various pharmaceuticals (Sobolov, Sun, & Cooper, 1998).
• Treatment and Prevention of Bacterial Infections: Compounds with sulfonyl, sulfinyl, or sulfenyl groups on benzene rings are useful in synthesis and have biological activity relevant to treating and preventing bacterial infections (Brown, 1996).
• Sulfonation Processes: These compounds are also involved in sulfonation processes, which are crucial in various chemical synthesis pathways (Brown, 1991).
• Extraction and Separation of Hydrocarbons: In a study on the separation of benzene and hexane, short alkyl chains in ionic liquids containing sulfonyl-amide groups led to more effective extraction, highlighting the potential of sulfonyl compounds in industrial applications (Arce, Earle, Rodríguez, & Seddon, 2007).
• Photocatalysis: A novel method for benzylic C-H bond sulfonylation under visible light was demonstrated, offering potential industrial applications (Gong, Chen, Lai, Cheng, Sun, & Wu, 2018).
• Herbicidal Activity: Sulfonanilides with pyrimidinyl-containing groups at the 2′-position, which may be related to sulfonyl benzene structures, show excellent pre-emergence herbicidal activity without harming rice plants (Yoshimura et al., 2011).
• Bioremediation: Bioremediation of groundwater contaminated with benzene and sulfolane can be achieved using specific bacteria, highlighting the environmental applications of such compounds (Yang et al., 2019).

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