1550-44-3 | 2,2-Difluoroethyl acetate

CAS:1550-44-3 | 2,2-Difluoroethyl acetate ,Description

2,2-Difluoroethyl acetate (DFA) is an organic compound with a wide range of uses in scientific research. It is a colorless liquid with a low boiling point and a faint odor. DFA is used in a variety of applications in the pharmaceutical, agricultural, and industrial sectors. It is also used in the synthesis of other compounds and as a solvent for a variety of organic compounds. In 
 

Scientific Research Applications

• Difluorocarbene Generation and Reactions:
  • Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate (MDFA) has been used as an efficient source of difluorocarbene, showing comparable reactivity to trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate (TFDA) under high concentration, high-temperature conditions (Eusterwiemann, Martínez, & Dolbier, 2012).
• Synthesis of Fluoroorganic Compounds:
  • 2-Bromo-3,3-difluoroallylic acetates can be prepared by reacting carbonyl compounds with 1-bromo-2,2-difluorovinyllithium, followed by acetylation, leading to the synthesis of 1,1-difluoroallenes (Yokota et al., 2009).
  • 2,2-Difluoroketene silyl acetal, derived from methyl difluoroiodoacetate, reacts with α,β-unsaturated carbonyl compounds to produce difluoro analogs of amino acids such as glutamic acid and lysine (Kitagawa, Hashimoto, Kobayashi, & Taguchi, 1990).
• Environmental Applications:
  • Studies on acetate-utilizing bacteria at environmental research sites have implications for understanding the use of acetates, including fluorinated compounds, in bioremediation and ecological studies (Kerkhof, Williams, Long, & McGuinness, 2011).
• Electrochemistry and Battery Technology:
  • Research on highly concentrated LiBF4/fluorinated ethyl acetate-based electrolyte solutions for lithium-ion batteries shows the relevance of fluorinated acetates in improving charge/discharge performance and safety of batteries (Doi, Fujii, & Inaba, 2021).
• Safety Assessments in Food Contact Materials:
  • Various studies have evaluated the safety of substances like perfluoro acetic acid and its derivatives, including 2,2-difluoroethyl acetate, for use in food contact materials (Flavourings, 2010, 2011, 2014).

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