1550-50-1 | 1,1,2,2-tetrafluoro-N,N-dimethylethanamine

CAS:1550-50-1 | 1,1,2,2-tetrafluoro-N,N-dimethylethanamine ,Description

1,1,2,2-Tetrafluoro-N,N-dimethylethanamine (TFDMEA) is an organic compound that has been used as a reagent in various laboratory experiments and applications, including the synthesis of pharmaceuticals and other compounds. It is a versatile, relatively inexpensive, and safe to use reagent that has attracted the attention of researchers in recent years. 
 

Scientific Research Applications

Fluorine Addition and Derivative Formation

The reaction of fluorine with various tolanes, including 1,1,2,2-tetrafluoro-1,2-diarylethanes, demonstrates the utility of 1,1,2,2-tetrafluoro-N,N-dimethylethanamine in the formation of fluorinated derivatives. These derivatives are important for their distinct chemical properties, especially in organic synthesis and materials science (McEwen, Guzikowski, & Wolf, 1984).

Chemical Synthesis and Compound Preparation

The preparation of various fluorinated compounds, such as 1,1,1,2-tetrafluoro2-iodoethane, is facilitated by using 1,1,2,2-tetrafluoro-N,N-dimethylethanamine. These methods are crucial in synthesizing specific fluorinated chemicals for further applications in various fields like pharmaceuticals and material science (Igumnov, 2022).

Exploration of Molecular Interactions

Studies on intramolecular charge resonance in dimer radical anions, including those of 1,1,2,2-tetrafluoro-N,N-dimethylethanamine derivatives, provide insights into molecular interactions and electron transfer processes. This knowledge is significant in the field of physical chemistry, particularly in understanding the behavior of radical anions and their potential applications in catalysis and organic electronics (Tojo, Fujitsuka, & Majima, 2012).

Development of Novel Chiral Agents

The synthesis of novel amine ligands from derivatives of 1,1,2,2-tetrafluoro-N,N-dimethylethanamine has led to the development of new chiral agents. These are particularly useful in asymmetric synthesis, an area of significant interest in the development of pharmaceuticals and fine chemicals (Yap et al., 2014).

Photoinduced Electron-Transfer Reactions

Research on the complexation and photoinduced electron-transfer reactions involving 1,1,2,2-tetrafluoro-N,N-dimethylethanamine derivatives is crucial in understanding light-induced chemical processes. This knowledge is applicable in photovoltaics, photocatalysis, and the development of light-activated molecular systems (Chen, Li, & Zhou, 1993).

Decomposition Mechanisms and Kinetics

Understanding the thermal decomposition mechanisms and kinetics of compounds like 1,1,2,2-tetrafluoro-N,N-dimethylethanamine is crucial in fields like materials science and chemical engineering, where thermal stability and decomposition products are critical factors (Chen & McQuaid, 2012).

Use as a Fluorinating Agent

1,1,2,2-Tetrafluoro-N,N-dimethylethanamine has been identified as an effective fluorinating agent, particularly for the conversion of alcohols into alkyl fluorides. This application is vital in synthetic chemistry for introducing fluorine atoms into organic molecules, often altering their physical and chemical properties significantly (Petrov et al., 2001).

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