157499-19-9 | 3-(Pentafluorophenyl)propyldimethylchlorosilane

CAS:157499-19-9 | 3-(Pentafluorophenyl)propyldimethylchlorosilane ,Description

3-(Pentafluorophenyl)propyldimethylchlorosilane (3-PFPPDMCS) is an organosilicon compound that has been used in a variety of scientific research applications. It is a colorless liquid with a molecular weight of 348.7 g/mol and a boiling point of 130 °C. 3-PFPPDMCS is a versatile reagent that can be used in organic synthesis, catalysis, and as a protecting group in peptide synthesis. It has also been used in the synthesis of various organosilicon compounds, such as polysiloxanes, polysulfides, and polysilazanes.
 

Scientific Research Applications

Synthesis and Reactivity

• 3-(Pentafluorophenyl)propyldimethylchlorosilane has been involved in the synthesis of pentafluorophenyl(fluoro)silanes, demonstrating reactivity with electrophiles and nucleophiles (Frohn et al., 1996).

Organosilicon Chemistry

• This compound has been used in organosilicon chemistry to create derivatives of 2-(pentafluorophenyl)ethylsilane, and to develop oligomeric siloxanes and polymers with pendant 2-(pentafluorophenyl)ethyl groups (Birchall et al., 1971).

Surface Modification

• It has been employed as a surface modifier for quartz and medical-grade stainless steel, showing potential for bioanalytical and biomedical applications (Blaszykowski et al., 2012).

Liquid Chromatography

• The compound is instrumental in the structural and chromatographic characterization of fluorinated mesoporous materials for use in near-ultrahigh-performance liquid chromatography (Ciogli et al., 2014).

Synthesis of Pentafluorophenylmethylamines

• It plays a role in the synthesis of pentafluorophenylmethylamines through a three-component coupling reaction (Dilman et al., 2005).

Characterization of Functionalized Surfaces

• 3-(Pentafluorophenyl)propyldimethylchlorosilane has been used in the characterization of functionalized silica surfaces by solid-state NMR and adsorption isotherm measurements, providing detailed insights into fluorinated stationary phases (Ashu-Arrah et al., 2013).

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