160976-02-3 | 4-Bromo-2,6-difluoroiodobenzene

CAS:160976-02-3 | 4-Bromo-2,6-difluoroiodobenzene,Description

4-Bromo-2,6-difluoroiodobenzene is a chemical compound with the molecular formula C6H2BrF2I. It has a molecular weight of 318.89. The compound is an off-white to light brown solid.

Physical And Chemical Properties Analysis

4-Bromo-2,6-difluoroiodobenzene has a melting point of 40-41°C and a predicted boiling point of 236.1±35.0 °C. The predicted density of the compound is 2.342±0.06 g/cm3. It is recommended to be stored in a dark place, sealed in dry, at 2-8°C.

Scientific Research Applications

Application

4-Bromo-2,6-difluoroiodobenzene is used as a raw material in the preparation of 4-bromo-2,6-difluorobenzonitrile. This compound is a midbody compound used in the preparation of liquid crystalline compounds.

Method of Application

The preparation method involves using tetrahydrofuran, potassium tert butoxide, petroleum ether, 3,5-difluorobromobenzene, DMF, and n-butyllithium. The raw materials are added to a three-necked flask according to the proportion, and are heated and refluxed for 10 hours at normal pressure.

Results

The method for preparing the 4-bromo-2,6-difluorobenzonitrile takes the 3,5-difluorobromobenzene as a basic raw material which is cheap, and the whole process engineering is low in cost, so the 4-bromo-2,6-difluorobenzonitrile is applicable to mass production.

Photoactive Materials

Application

4-Bromo-2,6-difluoroiodobenzene is used in the synthesis of a novel ortho-fluoroazobenzene, methyl 4-bromo-3-((2,6-difluorophenyl)diazenyl) benzoate. This compound is photoactive and has potential applications in separations, advanced sensors, drug delivery, data storage, and molecular switches.

Method of Application

The synthesis and structure of this novel ortho-fluoroazobenzene is described in the referenced study.

Results

The molecule is photoactive in solution, but the close-packed lattice appears to inhibit photo-induced structural reorganization in the crystalline state.

Safety And Hazards

4-Bromo-2,6-difluoroiodobenzene is classified as an irritant. It may cause respiratory irritation, skin irritation, and serious eye irritation. It is recommended to use only outdoors or in a well-ventilated area, avoid breathing dust/fumes, and wear protective gloves, protective clothing, eye protection, and face protection.

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