163702-07-6 | Methoxyperfluorobutane

CAS:163702-07-6 | Methoxyperfluorobutane ,Description

Methoxyperfluorobutane (MPFB) is a fluorinated hydrocarbon containing a single oxygen atom and four carbon atoms. It is a colorless, odorless gas with a boiling point of -3.6°C. MPFB is used in a variety of scientific and industrial applications, including as a propellant, a solvent, and a surfactant. It is also used in biomedical research and medical applications.
 

Scientific Research Applications

• Conversion to α-methylhexafluoroisobutyric acid fluoride: Methoxyperfluoroisobutene can be converted to α-methylhexafluoroisobutyric acid fluoride, offering a pathway to produce various fluorochemicals (Misaki, 1985).
• Replacement for n-hexane in HPLC applications: Ethoxynonafluorobutane, closely related to methoxyperfluorobutane, replaces n-hexane in normal-phase HPLC. It shows unique selectivity in chiral HPLC applications (Kagan, 2001) .
• Stability in mixture with isopropyl alcohol: Novec™ 71IPA DL, a mixture of methoxyperfluorobutane and isopropyl alcohol, is stable at ambient temperature. NMR studies provide insights into reactants and products over time (Knachel et al., 2013).
• Detection in plasma samples: ADONA, a compound related to methoxyperfluorobutane, has been detected in plasma samples near a PFOA production plant, highlighting its environmental and health relevance (Fromme et al., 2017).
• Inhaled analgesic properties: Methoxyflurane, an inhaled analgesic, has been used for over 40 years for pain management. It's effective, well-tolerated, and has a favorable safety profile (Porter et al., 2018).
• Preparation as alternative cleaning agents: Methoxynonafluorobutane and ethoxynonafluorobutane are studied as third-generation alternative cleaning agents, offering replacements for CFCs and HCFCs (Hwang et al., 2007).

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