167951-80-6 | 4-(Trifluoromethyl)-1,3-dioxolan-2-one

CAS:167951-80-6 | 4-(Trifluoromethyl)-1,3-dioxolan-2-one ,Description

4-(Trifluoromethyl)-1,3-dioxolan-2-one (TFMD) is an organic compound with the molecular formula C3H3F3O2. It is a colorless liquid with a boiling point of 101 °C and a melting point of -41 °C. TFMD is a versatile organic building block used in many organic syntheses, as it can be used to form a variety of compounds, including heterocycles and organofluorides. It is also used in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
 

Scientific Research Applications

• Lithium Battery Materials: The direct fluorination of 1,3-dioxolan-2-one has been successfully carried out, resulting in 4-fluoro-1,3-dioxolan-2-one, which is expected to be an additive for lithium ion secondary batteries. This also includes the development of trifluoromethanesulfonyl fluoride, an intermediate of lithium battery electrolyte (Kobayashi et al., 2003).
• Organic Synthesis: Research has been conducted on preparing 4-trifluoroethylidene-1,3-dioxolane derivatives using a new stable (trifluoromethyl)ethynylation reagent. This results in various perfluoroalkylated derivatives, demonstrating the versatility of 1,3-dioxolane in organic synthesis (Jeong et al., 2003).
• Fluoropolymer Synthesis: A study reported the synthesis of 4-Chloro-5-trifluoromethyl-2,2,4-trifluoro-1,3-dioxolane and its subsequent use in preparing high-Tg amorphous fluoropolymers. These fluoropolymers have potential applications in various high-performance materials (Russo & Navarrini, 2004).
• Chemical Protection of Compounds: The 1,3-dioxolanation of carbonyl compounds has been investigated, leading to the creation of 4-trimethylsilylmethyl-1,3-dioxolanes. These compounds are significant for the selective protection and regeneration of carbonyl compounds in chemical syntheses (Lillie & Avery, 1994).
• Building Blocks for Aliphatic Compounds: Synthesis of 5-trifluoromethyl-1,3-dioxin-4-ones has been used for the preparation of various trifluoromethylated aliphatic compounds. These compounds serve as versatile building blocks in organic chemistry (Iwaoka et al., 1992).
• Liquid Crystal Enhancement: The introduction of 1,3-dioxolane as a terminal group in tolane-liquid crystals was found to significantly increase positive dielectric anisotropy and birefringence. This enhances the performance of liquid crystals in display technologies (Chen et al., 2015).

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