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Purchase CAS:177985-33-0 | 2-CHLORO-5-FLUOROPHENYLACETIC ACID,view related peer-reviewed papers,technical documents,similar products,MSDS & more.Synthesis Analysis2-Chloro-5-fluorophenylacetic acid can be synthesized through a multi-step process involving amidation, etherification, Smiles rearrangement, chloroacetylation, cyclization, and hydrolysis. A specific example includes the synthesis of 2-{[(2-Chloro-6-fluorophenyl)amino]-5-methylphe...
2-Chloro-5-fluorophenylacetic acid can be synthesized through a multi-step process involving amidation, etherification, Smiles rearrangement, chloroacetylation, cyclization, and hydrolysis. A specific example includes the synthesis of 2-{[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid from p-Methylaniline and chloroacetic chloride, showcasing a methodological approach to obtaining halogenated phenylacetic acid derivatives with an overall yield of 66% (Liu Ying-xiang, 2007).
The safety information for “2-Chloro-5-fluorophenylacetic acid” indicates that it may be harmful if swallowed (Hazard Statements H302). Precautionary measures include avoiding breathing dust/fume/gas/mist/vapors/spray and using only outdoors or in a well-ventilated area.
Product Name: | 2-CHLORO-5-FLUOROPHENYLACETIC ACID |
Synonyms: | 2-(2-chloro-5-fluorophenyl)acetic acid;Benzeneacetic acid, 2-chloro-5-fluoro-;2-CHLORO-5-FLUOROPHENYLACETIC ACID ISO 9001:2015 REACH;2-CHLORO-5-FLUOROPHENYLACETIC ACID |
CAS: | 177985-33-0 |
MF: | C8H6ClFO2 |
MW: | 188.58 |
EINECS: | |
Product Categories: | |
Mol File: | 177985-33-0.mol |
2-CHLORO-5-FLUOROPHENYLACETIC ACID Chemical Properties |
Melting point | 114-115°C |
Boiling point | 289.3℃ |
density | 1.417 |
Fp | 128.8℃ |
storage temp. | Sealed in dry,Room Temperature |
pka | 3.85±0.10(Predicted) |