180287-02-9 | Methyl 2-fluoro-3-oxopentanoate

CAS:180287-02-9 | Methyl 2-fluoro-3-oxopentanoate ,Description

Methyl 2-fluoro-3-oxopentanoate (MFOP) is a synthetic compound that is used in a variety of laboratory experiments and research applications. It is a versatile compound that can be used as a starting material in organic synthesis, as a catalyst in reaction processes, and as a reagent in biochemical and physiological studies. MFOP is a relatively new compound, and its use in research is still in its early stages. 
 

Scientific Research Applications

• Fluorination of Methyl 3-Oxopentanoate (MOP) Using Difluorobis(fluoroxy)methane, BDM:
  • This study discusses the selective monofluorination of 1,3-dicarbonyls like diketones and ketoesters, specifically the fluorination of methyl 3-oxopentanoate (MOP) to produce methyl 2-fluoro-3-oxo-pentanoate (MFOP) with high conversion and selectivity (Bailey, Casteel, & Syvret, 2002).
• Determination of R- and S-3-methyl-2-oxopentanoate Enantiomers in Human Plasma:
  • This paper describes a method for determining the enantiomers of S- and R-3-methyl-2-oxopentanoate in physiological fluids, useful for isotope enrichment analysis (Schadewaldt, Wendel, & Hammen, 1996).
• The Metabolism of 4-methyl-2-oxopentanoate in Rat Pancreatic Islets:
  • Investigates how 4-methyl-2-oxopentanoate is metabolized in isolated pancreatic islets, showing its effects on islet-cell respiration, ketone-body formation, and biosynthetic activity (Hutton, Sener, & Malaisse, 1979).
• A Study of the Metabolism of [U-14C]3-methyl-2-oxopentanoate by Rat Liver Mitochondria:
  • Discusses the resolution of acyl-CoA intermediates in the degradation of 3-methyl-2-oxopentanoate and their regulation, using h.p.l.c. with continuous on-line monitoring (Causey, Middleton, & Bartlett, 1986).
• 2-Oxocarboxylic Acids and Function of Pancreatic Islets in Obese-hyperglycaemic Mice:
  • Investigates the effects of 2-oxocarboxylic acids like 2-oxopentanoate on insulin secretion and metabolism in the context of obesity and hyperglycemia in mice (Lenzen & Panten, 1980).

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