18599-22-9 | 4-Bromo-3,3,4,4-tetrafluoro-1-butene

CAS:18599-22-9 | 4-Bromo-3,3,4,4-tetrafluoro-1-butene ,Description

4-Bromo-3,3,4,4-tetrafluoro-1-butene (4-Br-T4F1B) is a member of the family of halogenated organic compounds known as tetrafluorobutenes. It is a colorless liquid with a boiling point of -37.5°C and a molecular weight of 205.9 g/mol. The chemical formula of 4-Br-T4F1B is C4H3BrF4. 4-Br-T4F1B has been widely used in various industrial and scientific applications due to its unique properties, such as its high reactivity and low boiling point.
 

Scientific Research Applications

• Multisubstituted Alkenes Synthesis: Sakaguchi et al. (2017) conducted a study on the transformation of 4-bromo-3,3,4,4-tetrafluoro-1-butene into multisubstituted alkenes. This process involved Heck reactions and Suzuki-Miyaura cross-coupling reactions, resulting in fluorinated materials with unique structural properties (Sakaguchi et al., 2017).
• Synthesis of Tetrafluoroethylenated Sugar Derivatives: Konno et al. (2013) developed synthetic approaches to create 2,3-dideoxy-2,2,3,3-tetrafluoropyranoses or azapyranoses using 4-bromo-3,3,4,4-tetrafluoro-1-butene. These compounds have potential applications in pharmaceuticals and materials science (Konno et al., 2013).
• Fluorinated Building Blocks: Linclau (2007) discussed the physical properties and preparative methods for compounds like 4-bromo-3,3,4,4-tetrafluoro-1-butene. These compounds are valuable as fluorinated building blocks in various chemical syntheses (Linclau, 2007) .
• Tetrafluoroethylenation of Aromatic Compounds: A study by Watanabe & Konno (2015) explored the treatment of 4-bromo-3,3,4,4-tetrafluorobut-1-ene with various aryl halides. This led to the synthesis of group-substituted aromatics, highlighting its potential in organic synthesis (Watanabe & Konno, 2015).
• Synthesis of Difluorohalobenzenes: Volchkov et al. (2021) used 4-bromo-3,3,4,4-tetrafluoro-1-butene in the synthesis of 2,3-difluorohalobenzenes. This process involved several steps, including halogenation and dehydrohalogenation, demonstrating its utility in complex organic syntheses (Volchkov et al., 2021).
• Stereoselective Epoxidation: Archelas et al. (1988) investigated the stereoselective epoxidation of 4-bromo-1-butene using alkene-utilizing bacteria. This research provides insight into biocatalytic processes and the influence of molecular structure on microbial activity (Archelas et al., 1988).

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