Cart (0)
No products in the cart.
Purchase CAS:186204-66-0,view related peer-reviewed papers,technical documents,similar products,MSDS & more.
2-(Difluoromethylsulfonyl)benzothiazole (DFMBT) is an important intermediate for the synthesis of pharmaceuticals, pesticides, and other fine chemicals. It is a versatile reagent that can be used in a variety of different synthetic pathways and can be used to synthesize a variety of different compounds. DFMBT is an imp...
2-(Difluoromethylsulfonyl)benzothiazole (DFMBT) is an important intermediate for the synthesis of pharmaceuticals, pesticides, and other fine chemicals. It is a versatile reagent that can be used in a variety of different synthetic pathways and can be used to synthesize a variety of different compounds. DFMBT is an important intermediate in the synthesis of pharmaceuticals, pesticides, and other fine chemicals. It is a versatile reagent that can be used in a variety of different synthetic pathways and can be used to synthesize a variety of different compounds.
Benzothiazole derivatives, including 2-(Difluoromethylsulfonyl)benzothiazole, have shown a wide range of pharmacological activities. These compounds are known for their antimicrobial, analgesic, anti-inflammatory, and antidiabetic activities. Notably, 2-arylbenzothiazoles are emerging as potential antitumor agents, with several compounds in this class being developed for cancer treatment. The structural simplicity of benzothiazoles and their derivatives allows for the development of chemical libraries that could aid in the discovery of new therapeutic entities (Kamal, Hussaini, & Malik, 2015).
Specific benzothiazole derivatives exhibit highly selective and potent antitumor properties both in vitro and in vivo. The mechanisms of action of these compounds involve cytochrome P450 1A1 induction and biotransformation, leading to the formation of active metabolites. Amino acid conjugation to the exocyclic primary amine function of certain benzothiazole derivatives has been used to improve solubility and stability. This approach has shown promise in the treatment of breast and ovarian tumors in preclinical studies (Bradshaw et al., 2002).
The synthesis and development of 2-substituted benzothiazole derivatives are areas of active research. Different methodologies have been developed using various catalysts to improve the selectivity, purity, and yield of these compounds. This is significant for the advancement of both synthetic and pharmaceutical chemistry, as benzothiazoles have potent pharmacological activities (Prajapati, Vekariya, Borad, & Patel, 2014).
Benzothiazole and its derivatives, including 2-(Difluoromethylsulfonyl)benzothiazole, are used globally for various therapeutic applications. These compounds display a wide spectrum of biological activities, encouraging medicinal chemists to synthesize novel therapeutic agents. The range of activities includes antitumor, antimicrobial, antidiabetic, anti-inflammatory, antiviral, and antioxidant properties (Sharma et al., 2013).
Research on benzothiazole-based medicinal chemistry is rapidly evolving. Benzothiazole derivatives and their metal complexes offer diverse pharmacological properties, making them important for the search for new therapeutics. These compounds have been used in practice to treat various diseases with high therapeutic efficacy, highlighting their potential as future drugs (Elgemeie, Azzam, & Osman, 2020).
Product Name : | 2-((Difluoromethyl)sulfonyl)benzo[d]thiazole | ||
CAS No. : | 186204-66-0 | Molecular Weight : | 249.26 |
MDL No. : | MFCD01831028 | Purity/ Specification : | |
Molecular Formula : | C8H5F2NO2S2 | Storage : | Inert atmosphere,2-8°C |
Boiling Point : | - |
GHS Pictogram : | |||
Signal Word : | Warning | Precautionary Statements : | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
UN# : | N/A | Class : | N/A |
Hazard Statements : | H315-H319 | Packing Group : | N/A |