202289-38-1 | Bis(2-methoxyethyl)aminosulfur trifluoride

CAS:202289-38-1 | Bis(2-methoxyethyl)aminosulfur trifluoride ,Description

Bis(2-methoxyethyl)aminosulfur trifluoride (BET-SF) is an organosulfur compound that is used in a variety of scientific and industrial applications. BET-SF is a colorless liquid with a pungent odor and is soluble in both polar and non-polar solvents. It is a strong oxidizing agent and is used as a catalyst in organic synthesis. BET-SF is also used in various biochemical and physiological studies due to its unique reactivity and selectivity.
 

Scientific Research Applications

Controlled Conversion in Organic Synthesis

• Synthesis of Phenylacetonitriles and Benzonitriles: Utilized for one-step synthesis of benzonitriles from phenylacetic acids, and extended to synthesize corresponding phenylacetonitriles (Kangani, Day, & Kelley, 2008).
• Facilitating Acyl Azides and Nitriles Synthesis: Effective in one-step synthesis of acyl azides from carboxylic acids, and also useful for optically active nitriles production (Kangani, Day, & Kelley, 2007).

Chemical Modification and Fluorination

• Fluorination of Thiocarbonyl Compounds: Used to convert various thiocarbonyl derivatives into gem-difluorides (Lal, Lobach, & Evans, 2000).
• Fluorination of Amino Alcohols and Diols: Demonstrated efficiency in synthesizing fluorinated chiral compounds (Singh & Shreeve, 2002).
• Direct Fluorination of Carbonyl Groups: Applied for fluorinating diaryl ketones and diaryl diketones to produce gem-difluorides and tetrafluorinated derivatives (Chang, Tewari, Adi, & Bae, 2008).

Reaction Mechanisms and Catalysis

• Reaction with Diaryl Sulfoxides: Studied for S-fluorination by activating sulfoxides, forming Ar2SF2 and Ar2SF(OTf) compounds (Laali & Borodkin, 2002).
• In Situ Generated Catalysts: Used in electrochemical oxidation for methanol oxidation catalysis (Tang, Wang, Chi, Sevilla, & Zeng, 2016).

Medicinal Chemistry and Pharmacology

• Modification of Natural Products: Modified triptolide and its analogues for enhanced cytotoxicity (Aoyagi et al., 2008).

Advanced Materials and Electrochemistry

• Ionic Liquid Based Hybrid Electrolyte: Utilized in lithium sulfur batteries (Yang et al., 2017).

More Information