2043-54-1 | 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane

CAS:2043-54-1 | 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane ,Description

Henicosafluoro-12-iodododecane (HFI) is an organic compound with a wide range of applications in scientific research. It has been used in a variety of experiments, ranging from biochemical and physiological studies to drug development and clinical trials. HFI is a fluorinated aliphatic hydrocarbon, containing a single carbon-carbon double bond and two fluorine atoms. The structure of HFI is unique in that it can be used as both a substrate and a catalyst in various reactions. Additionally, HFI has been found to be a useful reagent in the synthesis of various compounds, including drugs and other compounds of interest.
 

Scientific Research Applications

Environmental Detection and Analysis

1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane and similar polyfluorinated compounds are used as alternatives to harmful substances in various industries. Their environmental behaviors and potential adverse effects have been a subject of study. For instance, a study identified novel polyfluorinated ether sulfonates as alternatives to perfluorooctanesulfonate (PFOS) in China's electroplating industry. These compounds, including perfluorobutane, perfluorohexane, perfluorooctane, and perfluorodecanesulfonates, were detected in municipal sewage sludge samples, highlighting their widespread use and distribution (Ruan et al., 2015).

Synthesis of Liquid Crystals

In the field of materials science, such compounds are instrumental in synthesizing liquid crystals. A study focused on creating rodlike liquid crystals containing a single benzene unit, which included derivatives of highly fluorinated fatty acids. These liquid crystals exhibited unique thermotropic phases and their thermal stability increased with the length of the perfluorinated segment (Johansson et al., 1997).

Medical Imaging

In medical imaging, particularly in positron emission tomography (PET), these compounds play a vital role. A study described the use of spirocyclic hypervalent iodine(III) complexes for the radiofluorination of non-activated and hindered aromatics. This methodology was efficient for radiolabeling a diverse range of functionalized arenes and heteroarenes, crucial for developing new radiopharmaceuticals (Rotstein et al., 2014).

Nanostructure FabricationThe compound is also used in nanostructure fabrication. One study investigated the assembly of carbamate derivatives with partially fluorinated alkyl tails through air/water interfacial organization. This process led to the formation of nanofibers and nanospirals, which are of great interest in nanotechnology and material sciences [(Chen et al., 2007)]

Scientific Research Applications of 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane

Environmental and Industrial Applications

• Alternative to Harmful Chemicals: This compound, similar to other polyfluorinated compounds, has been identified as an alternative to perfluorooctanesulfonate (PFOS) in industries such as electroplating. A study highlighted the detection of these compounds in municipal sewage sludge in China, suggesting their wide use and potential environmental impact (Ruan et al., 2015).

Material Science

• Synthesis of Liquid Crystals: Highly fluorinated compounds are key in synthesizing liquid crystals. A study demonstrated the creation of rodlike liquid crystals containing a single benzene unit, where the length of the perfluorinated segment influenced the thermal stability of these crystals (Johansson et al., 1997).

Medical Imaging

• Radiofluorination in PET Imaging: The compound is used in radiofluorination techniques for PET imaging. Research has shown that spirocyclic hypervalent iodine(III) complexes, which are related to this compound, are effective in labeling a range of non-activated functionalized arenes and heteroarenes, essential for developing new radiopharmaceuticals (Rotstein et al., 2014).

Nanotechnology

• Fabrication of Nanostructures: The compound has been studied for its role in the assembly of nanostructures.

Scientific Research Applications of 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane

Environmental Impact and Alternative Usage

• Identification of Novel Polyfluorinated Ether Sulfonates: Research has identified novel polyfluorinated ether sulfonates, which include compounds like 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane, as alternatives to perfluorooctanesulfonate (PFOS) in industries such as electroplating. These compounds were detected in municipal sewage sludge samples in China, indicating their widespread usage and potential environmental distribution (Ruan et al., 2015).

Material Science and Chemistry

• Synthesis of Liquid Crystals: In the field of material science, such compounds are used in the synthesis of liquid crystals. They are key in creating rod-like liquid crystals containing single benzene units, where the thermal stability of these crystals is influenced by the length of the perfluorinated segment (Johansson et al., 1997).
• Medical Imaging Applications: In medical imaging, specifically in positron emission tomography (PET), these compounds play a significant role. They are used in the radiofluorination of non-activated and hindered aromatics, crucial for developing new radiopharmaceuticals (Rotstein et al., 2014).

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