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2062-98-8 | 2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride

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2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride (TFPF) is a fluorinated organic compound that has been used in a variety of scientific research applications. It is a colorless liquid that is soluble in both water and organic solvents. It is a versatile compound that has been used in the synthesis of a variet...

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CAS:2062-98-8 | 2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride ,Description

2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride (TFPF) is a fluorinated organic compound that has been used in a variety of scientific research applications. It is a colorless liquid that is soluble in both water and organic solvents. It is a versatile compound that has been used in the synthesis of a variety of fluorinated compounds and can also be used as a catalyst in organic synthesis.
 

Scientific Research Applications

 

Scientific Research Applications of 2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl Fluoride

  • Environmental Remediation and Wastewater Treatment

    • Mineralization and Defluoridation: A study by Shih, Tsai, and Huang (2013) in "Water research" explores the use of UV oxidation in a three-phase fluidized bed reactor for the mineralization and defluoridation of 2,2,3,3-Tetrafluoro-1-propanol (TFP), a compound related to 2,3,3,3-Tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride. They found this method effective for treating non-biodegradable fluorinated compounds in wastewater, achieving over 99.95% TOC removal and 99% fluoride removal (Shih, Tsai, & Huang, 2013).
  • Chemical Synthesis and Industrial Applications

    • Synthesis of Fluorocarbon Surfactants: Han et al. (2009) in "Colloids and Surfaces A" synthesized a series of perfluoro-2,5-dimethyl-3,6-dioxanonanoic acid ester fluorocarbon surfactants using 2,3,3,3-tetrafluoro-2-(1,1,2,3,3,3-hexafluoro-2-(heptafluoropropyloxy)-propoxy)-propionic acid fluoride. These surfactants exhibited low surface tension and significantly reduced the surface tensions of organic solvents (Han et al., 2009).
  • Polymer Technology

    • Development of Gel Polymer Electrolytes: Wehbi et al. (2019) in "Macromolecules" investigated vinylidene fluoride-based copolymers bearing pendant perfluoroalkyl ether groups, synthesized from a monomer including 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy]propyl 2-(trifluoromethyl)acrylate. These copolymers were used in gel polymer electrolytes, showing promising conductivity values for potential applications in energy storage devices (Wehbi et al., 2019).
  • Biomedical and Material Science

    • Hemocompatible and Antifouling Materials: Wen et al. (2010) in "Journal of Materials Science" developed a poly(ethylene–vinyl acetate) film with a fluorinated surface structure using 2,

    3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(heptafluoropropoxy)propoxy] propionyl fluoride. The film exhibited low hemolytic activity and no platelet adhesion, showing potential for use in biomedical applications due to its biocompatible surface and flexible substrate .

  • Environmental Impact Assessment

    • Perfluoroalkyl Substance Analysis: Kato et al. (2018) in "Chemosphere" developed methods for quantifying per- and polyfluoroalkyl substances (PFAS), including compounds related to 2,3,3,3-tetrafluoro-2-(perfluoropropoxy)propanoyl fluoride, in urine and serum. This study aids in understanding human exposure to these chemicals, crucial for environmental health and safety assessments (Kato et al., 2018).
  • Toxicology and Safety Studies

    • Toxicokinetics in Animals: Gannon et al. (2016) in "Toxicology" studied the absorption, distribution, metabolism, and excretion (ADME) of 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid ammonium salt in rats, mice, and monkeys. Understanding the toxicokinetics of related fluorinated compounds is vital for assessing their safety and environmental impact (Gannon et al., 2016).

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