208110-81-0 | 2-Fluoro-6-formylpyridine

CAS:208110-81-0 | 2-Fluoro-6-formylpyridine,Description

2-Fluoro-6-formylpyridine is a chemical compound used in the synthesis of fluoroheterocyclic aldoximes, which are therapeutic agents for the treatment of anti-cholinesterase poisoning.

Molecular Structure Analysis

The molecular formula of 2-Fluoro-6-formylpyridine is C6H4FNO. The exact molecular structure is not directly available, but similar compounds like 5-Fluoro-2-formylpyridine and 2-Formylpyridine have been analyzed.

Physical And Chemical Properties Analysis

The boiling point of 2-Fluoro-6-formylpyridine is predicted to be 192.4±20.0 °C, and its density is predicted to be 1.269±0.06 g/cm3.

Scientific Research Applications

• Fluorinated Pyridines Synthesis

  • Field : Organic Chemistry
  • Application : 2-Fluoro-6-formylpyridine is used in the synthesis of fluorinated pyridines. Fluoropyridines have reduced basicity and are usually less reactive than their chlorinated and brominated analogues.
  • Method : Fluorination of pyridine by complex AlF3 and CuF2 at 450–500 °C forms a mixture of 2-fluoropyridine and 2,6-difluoropyridine.
  • Results : The yield of 2-fluoropyridine and 2,6-difluoropyridine is 32% and 11% respectively.

• Proteomics Research

  • Field : Proteomics
  • Application : 2-Fluoro-6-formylpyridine is a specialty product for proteomics research applications.
  • Method : The specific methods of application in proteomics research are not detailed in the source.
  • Results : The outcomes of its use in proteomics research are not specified in the source.

Safety And Hazards

When handling 2-Fluoro-6-formylpyridine, it is advised to avoid breathing dust/fume/gas/mist/vapors/spray and to use only outdoors or in a well-ventilated area. It should be kept away from heat/sparks/open flames/hot surfaces.

Future Directions

Fluoropyridines, including 2-Fluoro-6-formylpyridine, have interesting and unusual physical, chemical, and biological properties owing to the presence of the strong electron-withdrawing substituent(s) in the aromatic ring. This has led to an increased interest in the development of fluorinated chemicals.

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