22515-16-8 | Diethyl 4,4-difluoroheptanedioate

CAS:22515-16-8 | Diethyl 4,4-difluoroheptanedioate ,Description

Diethyl 4,4-difluoroheptanedioate (DFH), also known as 4,4-difluoroheptanedioic acid diethyl ester, is a chemical compound commonly used in laboratory experiments. It is a colorless liquid with a boiling point of 88.2°C, and is soluble in a variety of organic solvents. DFH is used in a number of scientific research applications, including organic synthesis, medicinal chemistry, and analytical chemistry. 
 

Scientific Research Applications

Synthesis and Chemistry

• Diethyl 4-oxopimelate, a related compound, was used in the total, asymmetric synthesis of ethyl d-ido-4-heptulosuronate derivatives, highlighting its role in complex organic synthesis processes (Lemaire-Audoire & Vogel, 1999).
• In the field of palladium-catalyzed annulation, diethyl 2,2'-diiodo-4,4'-biphenyldicarboxylate, a compound structurally related to diethyl 4,4-difluoroheptanedioate, was used to produce 4-methylphenanthrenes, demonstrating its utility in complex chemical reactions (Mandal et al., 2000).

Material Science and Engineering

• Diethyl (difluoro(trimethylsilyl)methyl)phosphonate, another related compound, has been studied for its potential in difluoromethylenation of ketones, offering insights into its applications in material science and medicinal research (Wang, Cao, & Zhou, 2016).
• The radical polymerization of diethyl (Z,Z)-2,4-hexadienedioate in the crystalline state, a process closely related to the behavior of diethyl 4,4-difluoroheptanedioate, was investigated, yielding high-molecular-weight, stereoregular polymers, highlighting its potential in advanced material synthesis (Matsumoto et al., 1998).

Environmental Applications

• A study on diethyl phthalate, a compound similar in structure to diethyl 4,4-difluoroheptanedioate, focused on its degradation using CuFe2O4/MWCNTs and persulfate, showcasing the potential environmental applications of such compounds in pollutant degradation and environmental remediation (Zhang et al., 2016).

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