2343-89-7 | Methyl 2-fluoroacrylate

CAS:2343-89-7 | Methyl 2-fluoroacrylate ,Description

Methyl 2-fluoroacrylate (M2FA) is an organic compound with a wide range of applications in scientific research. It is a fluorinated derivative of acrylate and is used in a variety of laboratory experiments, including in the synthesis of other organic compounds, as a reagent for chemical reactions, and as a biological reagent for biochemical and physiological studies. M2FA is a versatile compound with many advantages, but also some limitations that must be taken into consideration when using it in laboratory experiments.
 

Scientific Research Applications

Synthesis of Novel Compounds

Methyl 2-fluoroacrylate serves as a key starting material in the synthesis of novel compounds. For instance, it has been used in the synthesis of 4-fluoro-2,4-methanoproline, a fluorinated analogue of naturally occurring 2,4-methanoproline, involving photochemical cyclization (Tkachenko et al., 2009). Additionally, it has been utilized in the efficient preparation of fluorovinyl-containing lactams through ring-closing metathesis of N-substituted 2-fluoroallylamides (Li et al., 2016).

Development of Fluorinated Polymers

Methyl 2-fluoroacrylate is crucial in the field of polymer chemistry, particularly in the anionic polymerization of fluorine-containing vinyl monomers. This process has been used to understand the general trends in the anionic polymerization of fluorinated acrylates, helping to create polymers with unique properties (Narita et al., 1993). Its application extends to the study of the free-radical polymerization kinetics of various acrylates, including methyl acrylate and ethyl α-fluoroacrylate (Degirmenci et al., 2009).

Fluorinated Nanoparticles for Molecular Delivery

The introduction of alkyl chain fluorination to polyacrylate nanoparticles has been studied, demonstrating that increasing fluorine content in these nanoparticles results in a decrease in size and changes in drug carrier properties. This research provides valuable insights for the application of fluorinated nanoparticles in molecular delivery (Labruère & Turos, 2012) .

Exploration in Material Science

Methyl 2-fluoroacrylate has contributed to advancements in material science, including the development of poly-2-fluoroacrylates for applications in optical materials, semiconductor techniques, and medical uses (Boguslavskaya, 1992). It has also played a role in creating fluorinated polymers for specialty coatings, demonstrating enhanced protective abilities against atmospheric corrosion (Malshe & Sangaj, 2005).

Dental Applications

In the field of dentistry, α-fluoro-substituted acryl polymers derived from methyl α-fluoroacrylate have been investigated as potential materials for denture bases. These polymers exhibit superior mechanical properties and varying water sorption characteristics, making them interesting candidates for dental applications (Kurata & Yamazaki, 1989).

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