2358-41-0 | 1-Fluoro-2-(trifluoromethylsulfonyl)benzene

CAS:2358-41-0 | 1-Fluoro-2-(trifluoromethylsulfonyl)benzene ,Description

1-Fluoro-2-(trifluoromethylsulfonyl)benzene, also known as 1-Fluoro-2-trifluoromethylbenzene sulfonate (FTB), is a fluorinated aromatic compound used in numerous scientific and industrial applications. FTB is an important intermediate in the synthesis of other fluorinated compounds, and is used in various areas such as in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. In addition, FTB has been used as a catalyst in organic reactions, and as a reagent in the synthesis of heterocyclic compounds. 
 

Scientific Research Applications

• Organic Electronics and Catalysis: Compounds like 3,4-fused 1,1-di-fluorocyclopropabenzenes, synthesized from fluoro benzenes, can be used in the production of fluoro cations. These cations have potential applications in organic electronics and catalysis (Müller & Rodriguez, 1986) .
• Chemical Reactivity and Synthesis: Electrophilic sulfonation of fluoro benzenes yields strong acidic polyfluoro benzene sulfonic acids. This process allows for the easy production of mono-, di-, and trithiols and sulfonic acids, which are important in chemical synthesis (Sartori, Cremer, & Johannsen, 1983).
• Solubility Studies: The solubility of compounds like 1-fluoro-4-(methylsulfonyl)benzene in organic solvents varies significantly, with the lowest solubility in ethanol. Such solubility studies are crucial in pharmaceutical and chemical industries for process optimization (Qian, Wang, & Chen, 2014).
• Novel Molecule Synthesis: Synthesis and nucleophilic aromatic substitution of compounds like 3-fluoro-5-nitro-1-(pentafluorosulfanyl)benzene can lead to the creation of novel (pentafluorosulfanyl)benzenes with unique properties (Ajenjo, Greenhall, Zarantonello, & Beier, 2016).
• Catalysis: Bismuth tris-trifluoromethanesulfonate demonstrates high catalytic activity in the Friedel-Crafts acylation reaction. This property is valuable for the synthesis of various aromatic compounds (Desmurs, Labrouillere, Roux, Gaspard, Laporterie, & Dubac, 1997).
• Fluorescence Studies: Fluoro(trifluoromethyl)benzenes show unique fluorescence spectra and quenching of singlet state emission, which is significant in photophysical research (Al-ani, 1973).
• Electron Capture Studies: Dissociative electron attachment studies on halocarbon-derivatives of nitro-benzene, including fluoro(trifluoromethyl)benzenes, reveal efficient capture of thermal electrons. Such studies are important in understanding the electronic properties of these compounds (Wnorowska, Kočišek, & Matejčík, 2014).
• Environmental Remediation: Compounds related to fluoro(trifluoromethyl)benzenes, like PFOS and PFOA, can be effectively reduced in groundwater through heat-activated persulfate oxidation. This method is promising for in-situ groundwater remediation (Park, Lee, Medina, Zull, & Waisner, 2016).

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