247069-27-8 | 2,6-Diamino-3,5-difluoropyridine

CAS:247069-27-8 | 2,6-Diamino-3,5-difluoropyridine ,Description

2,6-Diamino-3,5-difluoropyridine, also known as 2,6-DDF, is an organic compound that is widely used in the synthesis of pharmaceuticals and other organic compounds. It is a versatile reagent used for a variety of synthetic reactions and has been the subject of much research in recent years. 
 

Scientific Research Applications

• Energetic Materials Research:
  • Hollins et al. (1996) demonstrated that 2,6-Diamino-3,5-dinitropyridine 1-oxide, a related compound, shows properties like high density, thermal and chemical stability, required for new insensitive energetic materials due to its planar structures and hydrogen bonding (Hollins et al., 1996) .
  • Liu Zu-liang (2009) studied the synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide (ANPyO) and its properties as a potential energetic material (Liu Zu-liang, 2009).
• Chemical Synthesis and Molecular Geometry:
  • Orrell and Šik (1975) analyzed the molecular geometry of 2,6-difluoropyridine, revealing ring distortion near fluorine substituents (Orrell & Šik, 1975).
  • Dewberry et al. (2017) observed that fluorination in ortho positions of pyridine causes CO2 to rotate out of the plane, impacting intermolecular interactions (Dewberry et al., 2017).
• Material Science Applications:
  • Chen and Flowers (1980) conducted controlled chlorination of 2,6-diaminopyridine for the synthesis of various tetrahalogenopyridines, relevant in material science (Chen & Flowers, 1980).
  • Rauckman and Roth (1980) explored electrophilic substitution of 2,4-diaminopyridine, a related compound, for creating benzyl and halo derivatives, potentially useful in material science (Rauckman & Roth, 1980).
• Optimization of Synthetic Technologies:
  • Li Sheng-song (2010) improved the synthesis of 3,5-dichloro-2,6-difluoropyridin-4-amine, a compound structurally similar to 2,6-Diamino-3,5-difluoropyridine, demonstrating potential for large-scale production (Li Sheng-song, 2010).
• Compatibility with Other Materials:
  • Xi Li et al. (2016) studied the compatibility of ANPyO with other energetic materials, which is crucial for safe handling and storage in various applications (Xi Li et al., 2016).
• Organometallic Chemistry:
  • Schlosser and Rausis (2004) demonstrated the synthesis of various 2,6-difluoropyridine derivatives using modern organometallic methods, highlighting its versatility in this field (Schlosser & Rausis, 2004) .

More Information