2641-34-1 | Hexafluoropropene oxide trimer

CAS:2641-34-1 | Hexafluoropropene oxide trimer ,Description

Hexafluoropropene oxide trimer, also known as HFPO-T, is a versatile and widely used chemical compound with a wide range of applications in the chemical and biomedical industries. HFPO-T is a colorless, odorless, and non-flammable gas with a molecular weight of about 180 g/mol. Its unique structure and properties make it a valuable tool for the synthesis of a variety of organic compounds, as well as for the study of biochemical and physiological effects. 
 

Scientific Research Applications

Synthesis and Chemical Reactions

• Epoxidation and Reactions with Nucleophilic and Electrophilic Agents: Hexafluoropropene oxide trimer can undergo epoxidation using aqueous sodium hypochlorite, leading to high yields of α-oxides. This process involves reactions with various nucleophilic (e.g., CsF, Et3N, LiAlH4, CH3ONa) and electrophilic agents (e.g., SbF5, HSO3F). The effect of steric and electronic factors on the reactivity of these compounds is notable (Zapevalov et al., 1985) .

Environmental Degradation and Ecology

• Degradation in Nanofiltration Concentrate: Hexafluoropropene oxide trimer acid, as an alternative to perfluorooctanoic acid (PFOA), can undergo degradation under UV/persulfate conditions. This degradation follows a pathway of trimer acid to dimer acid. The study also highlights the ecological risks and suggests UV/sulfite as a potential complementary technology for nanofiltration in removing these contaminants from drinking water (Bao et al., 2020).

Chemical Interactions and Configurations

• Interaction with Ammonia and Primary Amines: Hexafluoropropene trimers react with primary amines to form enamines and enimines, products resulting from indirect substitution of fluorine atoms. The adduct with ammonia and the intramolecular cyclization of synthesized compounds to azetines and azetidines has been studied, providing insights into the chemical behavior of hexafluoropropene trimers (Del'tsova et al., 1996) .

Industrial and Synthetic Applications

• Oligomerisation and Carbon-Carbon Bond Fission: The oligomerisation of hexafluoropropene, catalyzed by fluoride ion, leads to the formation of dimers and trimers. Interestingly, one of the trimers undergoes fission of a carbon-carbon bond upon treatment with fluoride ion, forming a dimer and a heptafluoro-isopropyl carbanion. This process demonstrates the potential for controlled synthesis and modification of hexafluoropropene-derived materials (Brunskill et al., 1970).

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