287966-55-6 | 1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride

CAS:287966-55-6 | 1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride ,Description

1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride, also known as Dihydropyrimidinone or Hantzsch dihydropyridine, is a heterocyclic organic compound with a molecular formula of C8H14FN. It has been widely used in scientific research due to its unique chemical properties, such as its ability to act as a reducing agent and its potential as a precursor for the synthesis of various pharmaceuticals and agrochemicals.
 

Scientific Research Applications

• Synthesis and Structural Analysis:
  • A study by Sukach et al. (2015) focused on synthesizing trifluoromethylated analogues of 4,5‐dihydroorotic acid, which involve reactions with pyrimidin-2(1H)-ones, closely related to 1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride (Sukach et al., 2015).
  • Tian et al. (2014) examined the reaction between 1,3-dimethyl-1H-imidazolium iodide and AgF, resulting in hydrofluorides, which provides insights into the reactivity and potential applications of hydrofluoride derivatives (Tian et al., 2014).
• Anticancer Activity:
  • Research by Abdellatif et al. (2014) explored the synthesis of pyrazolo[3,4-d]pyrimidin-4-one derivatives and their anticancer activity. This study indicates the potential biomedical applications of pyrimidinone derivatives (Abdellatif et al., 2014).
• Chemical Properties and Reactions:
  • The study by Kodape et al. (2012) demonstrated the efficient aromatization of dihydropyrimidin-2(1H)-ones, which are structurally related to 1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride, using iodine under microwave irradiation (Kodape et al., 2012).
• Molecular Structure Investigation:
  • The work of Mansour and Ghani (2013) on sulfamethazine Schiff-base, involving pyrimidin-2-yl derivatives, provides insights into the molecular structure and spectroscopic properties, which could be relevant for understanding the properties of related compounds (Mansour & Ghani, 2013).

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