3109-99-7 | 2-Fluoro-2-methylpropan-1-ol

CAS:3109-99-7 | 2-Fluoro-2-methylpropan-1-ol ,Description

2-Fluoro-2-methylpropan-1-ol, also known as FMPA, is a colorless, volatile liquid that is used in a variety of scientific and industrial applications. It is a versatile compound that can be used for synthesis, as a reagent, and as an intermediate for various reactions. It is used in a variety of industries, including pharmaceuticals, agrochemicals, and petrochemicals. FMPA is also used in the manufacture of perfumes, dyes, and other compounds.
 

Scientific Research Applications

Biofuel Production

2-Fluoro-2-methylpropan-1-ol, also known as 2-methylpropan-1-ol, is being studied for its potential in biofuel production. Bastian et al. (2011) explored the conversion of glucose to isobutanol, a biofuel candidate, in Escherichia coli. Their work focused on overcoming cofactor imbalances to achieve anaerobic isobutanol production at a high yield, marking a significant step in biofuel commercialization (Bastian et al., 2011).

Chemical Reactions

Yangjeh and Gholami (2003) investigated the reaction kinetics of 1-fluoro-2, 4-dinitrobenzene with piperidine in solutions of alcohols, including 2-methylpropan-2-ol. Their research contributes to understanding the polarity and reactivity in such reactions, which is essential for developing new synthetic pathways in chemistry (Yangjeh & Gholami, 2003).

Fluorination Studies

Burdon et al. (1977) conducted a study on the fluorination of 2-methylpropane, leading to the production of a variety of fluorinated compounds. This research is crucial for understanding the fluorination processes of hydrocarbons, which has implications in materials science and chemical synthesis (Burdon et al., 1977).

Medical Chemistry

Pero et al. (1977) synthesized and studied the effects of various esters of 3-fluoropropan-2-one, including their structure-activity relationships in mice. These findings have implications in medicinal chemistry, particularly in understanding the toxicity and potential therapeutic applications of fluorinated compounds (Pero et al., 1977).

HIV-1 Transmission Prevention

Sawada et al. (1998) explored the use of fluoroalkylated 2-acrylamido-2-methylpropanesulfonic acid oligomers in gels as potential inhibitors of HIV-1 replication. This research holds promise for developing new methods to prevent HIV-1 transmission (Sawada et al., 1998).

Radiosynthesis in PET Tracers

Rotteveel et al. (2017) investigated the synthesis of 1-iodo-2-[11 C]methylpropane and 2-methyl-1-[11 C]propanol for use in positron emission tomography (PET) tracers. This research is significant in the field of nuclear medicine, particularly in improving the tools available for diagnostic imaging (Rotteveel et al., 2017).

Thermodynamic Studies

Connett (1972) measured equilibrium constants for the dehydrogenation of 2-methylpropan-1-ol, contributing valuable data to the field of chemical thermodynamics. This kind of research aids in understanding the fundamental properties of chemical reactions (Connett, 1972).

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