312-68-5 | 3-Fluoropropyl 4-methylbenzenesulfonate

CAS:312-68-5 | 3-Fluoropropyl 4-methylbenzenesulfonate ,Description

3-Fluoropropyl 4-methylbenzenesulfonate (3-FPMS) is a synthetic chemical compound that has become increasingly important in the scientific research community. It is a colorless, odorless, crystalline solid that is soluble in water and organic solvents. 3-FPMS is used in a variety of applications due to its unique properties, such as its low toxicity and wide range of solubility. It has been used in the synthesis of pharmaceuticals, in the production of pesticides and herbicides, and in the study of biochemical and physiological processes. 
 

Scientific Research Applications

1. Imaging Agents in Nuclear Medicine

3-Fluoropropyl 4-methylbenzenesulfonate has been utilized in the synthesis of radiolabeled compounds for nuclear medicine. Specifically, it has been used to develop (18)F-labelled metomidate analogues for adrenocortical imaging. These analogues have shown potential as imaging agents due to their high degree of specific adrenal binding and favorable organ uptake ratios, indicating their usefulness in identifying adrenal gland abnormalities (Erlandsson et al., 2009).

2. Organic Synthesis

The compound plays a significant role in organic synthesis. For example, it has been involved in the synthesis of various intermediates and derivatives. Such applications include the production of 3-Hydroxy-2-iodophenyl-(4-methylbenzenesulfonate) via a multi-step procedure, indicating the versatility of 3-Fluoropropyl 4-methylbenzenesulfonate in organic chemistry (Pan et al., 2020).

3. Structural and Spectroscopic Analysis

Studies have also been conducted on the structural and spectroscopic properties of related compounds like 4-methylbenzenesulfonate. These investigations, which include ab initio molecular orbital study and spectroscopic analysis, contribute to a deeper understanding of the molecular structure and characteristics of sulfonate derivatives, which is fundamental in various scientific research areas (Ristova et al., 1999).

4. Development of Multifunctional Drug Candidates

3-Fluoropropyl 4-methylbenzenesulfonate has been involved in the development of novel drug candidates. For instance, its derivatives have been used in synthesizing compounds with multiple receptor binding affinities, indicating its potential in creating multifunctional treatments for neuropsychiatric and neurological disorders (Li et al., 2014).

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