327-54-8 | 1,2,4,5-Tetrafluorobenzene

CAS:327-54-8 | 1,2,4,5-Tetrafluorobenzene ,Description

1,2,4,5-Tetrafluorobenzene (TFB) is an organic compound with the chemical formula C6F4H2. It is a colorless liquid with a sweet, pungent odor. It is a halogenated aromatic compound, and it is an important intermediate for the synthesis of many organic compounds. It is also used in the production of pharmaceuticals, agricultural chemicals, and industrial chemicals. TFB has a wide range of applications in the fields of chemistry, medicine, and biochemistry.
 

Scientific Research Applications

Molecular Structure and Electron Diffraction Studies

1,2,4,5-Tetrafluorobenzene has been a subject of study for understanding its molecular structure through electron diffraction and ab initio calculations. These studies provide insights into the geometric parameters of the benzene ring, bond lengths, and angles, which are crucial for understanding the chemical behavior and reactivity of this compound (Schei, Almenningen, & Almlöf, 1984).

Crystal Structure Analysis

Research has also been conducted on the crystal structure of 1,2,4,5-tetrafluorobenzene and its interactions with other molecules. Studies focus on the molecular packing, intermolecular interactions such as hydrogen bonding, and the influence of these factors on the crystal properties (Thakur et al., 2010) .

Application in Chromophores

1,2,4,5-Tetrafluorobenzene has been utilized as a central acceptor moiety in the design of chromophores. These compounds have applications in fields such as nonlinear optics and photovoltaics. Research in this area focuses on synthesizing novel chromophores and investigating their electronic and optical properties (Kulhanek et al., 2014) .

Infrared Spectroscopy and Cluster Studies

Infrared spectroscopy has been used to study clusters formed by 1,2,4,5-tetrafluorobenzene with other molecules. These studies help in understanding the nature of intermolecular interactions, such as hydrogen bonding, within these clusters (Venkatesan, Fujii, & Mikami, 2005) .

Photocatalytic Applications

The photocatalyzed oxidation of benzylic compounds using 1,2,4,5-tetrafluorobenzene has been explored as a route to synthesize electron-deficient benzylic fluorides. This research highlights the potential of 1,2,4,5-tetrafluorobenzene in photocatalysis and organic synthesis (Bloom, McCann, & Lectka, 2014).

Thermodynamic Properties

Studies on the thermodynamic properties of 1,2,4,5-tetrafluorobenzene, including measurements of heat capacities and phase transitions, provide valuable data for its application in various chemical processes (Andon & Martin, 1973).

Synthesis of Polyfluorinated Organic Compounds

Research literature has been reviewed to reveal methodologies related to the chemical transformations of 1,2,4,5-tetrafluorobenzene in the synthesis of polyfluorinated organic compounds, highlighting its importance as a chemical building block (Sapegin & Krasavin, 2018).

Vibrational Spectroscopy Studies

The study of the butterfly vibrational mode in 1,2,4,5-tetrafluorobenzene using pulsed field ionization-zero kinetic energy photoelectron spectroscopy provides insights into the molecular structure and dynamics of this compound (Takazawa & Fujii, 2000).

NMR Spectroscopy

NMR spectroscopy has been used to study the anisotropies of indirect nuclear spin-spin couplings in tetrafluorobenzenes, including 1,2,4,5-tetrafluorobenzene. This research contributes to the understanding of the electronic structure of these molecules (Gerritsen et al., 1972).

Organomercury Compound Synthesis

The synthesis and characterization of organomercury compounds from 1,2,4,5-tetrafluorobenzene have been explored, demonstrating its utility in the preparation of complex organometallic compounds (Albrecht & Deacon, 1972).

Conducting Polymer Research

1,2,4,5-Tetrafluorobenzene has been used in the synthesis of fluorine compounds relevant to conducting polymer research. This highlights its potential in the development of fluorinated materials for electronics and other applications (Krebs & Jensen, 2003).

Synthesis of Metal-Organic Frameworks

Research on the synthesis of tetrafluoroterephthalic acid from 1,2,4,5-tetrafluorobenzene has implications for the construction of new coordination polymers and metal-organic frameworks, expanding its utility in materials science (Orthaber et al., 2010).

Electronic Spectroscopy of Cations

Studies on the electronic spectra of 1,2,4,5-tetrafluorobenzene cations, produced by pulsed glow discharge, contribute to the understanding of the electronic structure and photophysical properties of fluorinated aromatic compounds (Nibu, Fujii, & Shimada, 1999).

Microwave Spectroscopy

The investigation of the microwave spectrum, dipole moment, and centrifugal distortion constants of 1,2,4,5-tetrafluorobenzene provides essential data for its characterization and applications in molecular spectroscopy (Sharma & Doraiswamy, 1977).

Rhodium-Catalyzed Substitution Reactions

The use of 1,2,4,5-tetrafluorobenzene in rhodium-catalyzed substitution reactions with disulfides has been studied, showcasing its reactivity and potential in organic synthesis (Arisawa, Suzuki, Ishikawa, & Yamaguchi, 2008).

More Information