345-92-6 | 4,4'-Difluorobenzophenone

CAS:345-92-6 | 4,4'-Difluorobenzophenone ,Description

4,4'-Difluorobenzophenone (4,4'-DFBP) is an organic compound belonging to the class of benzophenones. It is a colorless solid that is used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a photochemical initiator. 4,4'-DFBP is a widely used compound in research laboratories, and is used for a variety of purposes including in the synthesis of pharmaceuticals, organic materials, and polymers.
 

Scientific Research Applications

Synthesis Methods and Properties4,4'-Difluorobenzophenone is a significant fluorine-containing fine chemical and pharmaceutical intermediate. Various synthesis methods for 4,4'-Difluorobenzophenone have been explored, including Fridel-Crafts alkylation hydrolysis, Fridel-Crafts acylation, halogen substitution, diazotization oxidation, catalytic carbonylation, and others. These methods highlight its versatility in chemical synthesis (Z. Hen, 2014).

Solubility and Thermodynamic PropertiesResearch on the solubility of 4,4'-Difluorobenzophenone in various solvents has been conducted. The study found that its solubility increases with temperature in a range of solvents. This research is crucial for understanding its behaviors in different solvent environments, which is vital for its purification and crystallization (Mingyan Li et al., 2020).

Polymer Synthesis4,4'-Difluorobenzophenone plays a critical role in the synthesis of aromatic poly(ether ketone)s. It has been used in bulk condensations with silylated bisphenols, leading to the creation of glassy polymers that are soluble in organic solvents. These polymers have diverse applications in engineering and materials science due to their solubility and thermal stability (H. Kricheldorf & G. Bier, 1984).

Electro-Optical ApplicationsIn the field of electro-optics, 4,4'-Difluorobenzophenone has been utilized to enhance the properties of polymer-stabilized blue phase liquid crystals. Its inclusion in these materials can effectively reduce operation voltage and improve the electro-optical response, demonstrating its potential in display technologies (Po-Chang Wu et al., 2017).

Catalysis in Chemical ReactionsThe compound has been used as a reactant in catalyzed reactions, such as those involving acidic imidazolium chloroaluminate ionic liquid, demonstrating its importance in various chemical synthesis processes (Wu Lichun & Wan Ming-hui, 2009).

Fuel Cell ApplicationsIn fuel cell technology, 4,4'-Difluorobenzophenone is used in the synthesis of novel polymers, such as sulfonated poly(ether ether ketone), which shows high selectivity and is essential for direct methanol fuel cell applications. This highlights its role in advancing sustainable energy technologies (Hongtao Li et al., 2009).

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