355-43-1 | Perfluorohexyl iodide

CAS:355-43-1 | Perfluorohexyl iodide ,Description

Perfluorohexyl iodide (PFHxI) is a halogenated organic compound with a wide range of applications in the scientific research and industrial fields. It is an alkyl iodide with a perfluorinated hexyl group, and is mainly used as a reagent in organic synthesis. Its unique properties make it an ideal compound for a variety of research applications, ranging from biochemistry to environmental toxicology. 
 

Scientific Research Applications

Halogen Bonding and Electrostatic Interactions

• Non-Covalent Interactions: Perfluorohexyl iodide forms complexes with hydrogen-bond acceptors, providing insights into halogen bonding, hydrogen bonding, desolvation, and electrostatics of non-covalent interactions (Cabot & Hunter, 2009).

Synthesis and Characterization of Novel Compounds

• Methacryloyl Monomers: It's used as a raw material in preparing methacryloyl monomers with aromatic rings and perfluorocarbon side chains, leading to new materials with specific properties (Wang Ming-gang, 2012).
• Polymerization Studies: Perfluorohexyl iodide plays a role in the formation of 3-(perfluorohexyl)prop-1-ene and related compounds under varying reaction conditions, contributing to material science and polymer chemistry (Napoli & Bertani, 2001).

Reactivity in Organic Synthesis

• Reactivity with Amides and Esters: The compound reacts with N,N-disubstituted amides or ethyl formate to produce perfluorinated carbonyl compounds, demonstrating its efficacy in organic synthesis (Benefice-Malouet & Commeyras, 1995).

Application in Emulsion and Surface Studies

• Perfluorocarbon Emulsions: In biomedical and pharmaceutical research, perfluorohexyl iodide is utilized in water emulsions stabilized by phospholipids. This has implications for drug delivery systems and medical imaging (Vleeschauwer & Meeren, 1998).

Role in Chemical Reactions

• Sulfinatodehalogenation Reactions: The compound's role in sulfinatodehalogenation reactions offers insights into solvent effects and reaction conditions, enhancing understanding of reaction mechanisms (Wu & Chen, 2010).
• Polymerization in Supercritical CO2: It's used to control molecular weight in vinylidene fluoride polymerizations, contributing to the field of polymer science (Beuermann & Imran-ul-haq, 2007).

Electrochemical Studies

• Reduction on Mercury: The electrochemical reduction behavior of perfluorohexyl iodide on mercury electrodes offers insights into electrochemistry and material science (Calas, Moreau, & Commeyras, 1977).

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