358-64-5 | Tris(2,2-difluoroethyl)phosphate

CAS:358-64-5 | Tris(2,2-difluoroethyl)phosphate ,Description

Tris(2,2-difluoroethyl)phosphate (TDEFP) is an organophosphate compound that has been widely used in a variety of scientific research applications. It is an important tool in the study of biochemical and physiological effects and has been used to develop a range of lab experiments. Furthermore, it will provide an overview of potential future directions for research. It is a rare, stable and flame-retardant fluorophosphate electrolyte additive with promising development prospects.
 

Scientific Research Applications

Flame Retardant Properties

Tris(2,3-dibromopropyl) phosphate, closely related to Tris(2,2-difluoroethyl)phosphate, has been extensively used as a flame-retardant additive for textiles. Its ability to induce mutations in bacterial strains like Salmonella typhimurium highlights its potential genetic impacts, which is a crucial aspect in understanding its broader applications and safety concerns (Prival et al., 1977).

Biotransformation and Environmental Impact

Research on various phosphate flame retardants (PFRs), including compounds structurally similar to Tris(2,2-difluoroethyl)phosphate, has shown their presence in indoor environments at high levels. The study of their biotransformation, particularly through human liver fractions, is vital for understanding their bioavailability and toxicity (Van den Eede et al., 2013).

Microbial Degradation

The degradation of chlorinated flame retardants, similar in structure to Tris(2,2-difluoroethyl)phosphate, by bacterial strains indicates potential avenues for bioremediation of environments contaminated with such compounds. This approach is critical for managing environmental pollution and understanding microbial interactions with these substances (Takahashi et al., 2010).

Chemical Reactivity and Applications

The use of Tris(trifluoroethyl)phosphate for the alkylation of aromatic amines, closely related to Tris(2,2-difluoroethyl)phosphate, showcases its reactivity and potential use in synthetic chemistry. This property can be harnessed for various industrial and research applications, such as developing new compounds or materials (Bissell, 1977) .

Human Exposure and Health Implications

Studies examining the presence of organophosphate flame retardants (OPFRs), including compounds similar to Tris(2,2-difluoroethyl)phosphate, in human urine indicate widespread exposure. Such research provides insights into exposure patterns and potential health implications, emphasizing the need for further investigation into the effects of these substances (Ospina et al., 2018).

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