36556-50-0 | 2,3-Dichlorofluorobenzene

CAS:36556-50-0 | 2,3-Dichlorofluorobenzene,Description

2,3-Dichlorofluorobenzene is a chemical compound with the molecular formula C6H3Cl2F. It has a molecular weight of 164.99 g/mol. The IUPAC name for this compound is 1,2-dichloro-3-fluorobenzene.

Molecular Structure Analysis

The molecular structure of 2,3-Dichlorofluorobenzene consists of a benzene ring with two chlorine atoms and one fluorine atom attached to it. The InChI representation of the molecule is InChI=1S/C6H3Cl2F/c7-4-2-1-3-5(9)6(4)8/h1-3H.

Physical And Chemical Properties Analysis

2,3-Dichlorofluorobenzene is a liquid at room temperature. It has a density of 1.4±0.1 g/cm³. The boiling point of this compound is 175.8±20.0 °C at 760 mmHg. It has a vapor pressure of 1.5±0.3 mmHg at 25°C. The enthalpy of vaporization is 39.5±3.0 kJ/mol. The compound has a flash point of 61.0±15.2 °C.

Scientific Research Applications

Organic Intermediate in Pharmaceutical Synthesis

2,3-Dichlorofluorobenzene serves as an important organic intermediate in the synthesis of pharmaceutical products. Specifically, derivatives such as 2,4-dichlorofluorobenzene have been used in synthesizing ciprofloxacin, a broad-spectrum antibiotic. The increasing demand for ciprofloxacin has, in turn, led to a growing need for 2,4-dichlorofluorobenzene, highlighting its significance in the pharmaceutical industry (Wang Guo-xi, 2004); (Xiao You-jun, 2008).

Antibacterial and Antifungal Studies

The antibacterial and antifungal properties of 2,3-Dichlorofluorobenzene derivatives have been studied. These derivatives demonstrated activity against various bacteria and fungi, indicating potential applications in developing new antimicrobial agents (H. Katırcıoğlu, E. Loğoğlu, Tahir Tilki, A. Öktemer, 2007) .

Chemical Process Optimization

Research has been conducted to optimize chemical processes involving 2,3-Dichlorofluorobenzene. For instance, studies on acetylation technology have sought to enhance the yield and purity of related compounds, which is crucial for industrial-scale production (R. Gan, 2006).

Physical Properties Analysis

Understanding the physical properties of 2,3-Dichlorofluorobenzene is vital for its application in various industrial processes. Studies on its density, viscosity, vapor pressure, and vapor-liquid equilibria provide essential data for engineering design and distillation processes (Jinbei Yang, Shu-ying Han, Qiuju Xu, Meiqiong Yu, 2020).

Environmental Impact and Biodegradation

Research on the environmental impact and biodegradation pathways of dichlorofluorobenzenes, including 2,3-Dichlorofluorobenzene, is crucial for addressing contamination concerns. Studies on aerobic biodegradation have revealed the feasibility of using biological methods to remediate contaminated sites, highlighting the importance of understanding and mitigating the environmental impacts of these compounds (Mallory L Palatucci, Lisa A. Waidner, E. E. Mack, J. Spain, 2019).

Safety And Hazards

The safety information available indicates that 2,3-Dichlorofluorobenzene may cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Precautionary measures include avoiding breathing dust/fume/gas/mist/vapors/spray (P261) and rinsing cautiously with water for several minutes in case of contact with eyes (P305 + P351 + P338).

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