372-93-0 | 4-Fluoro-1-butanol

CAS:372-93-0 | 4-Fluoro-1-butanol ,Description

4-Fluoro-1-butanol (4FB) is an organic compound with a molecular formula of C4H9FO. It is a colorless liquid with a characteristic odor and is a member of the group of compounds known as fluoroalcohols. 4FB is an important intermediate in many chemical reactions, and has been used in a variety of scientific research applications. Additionally, it will discuss the advantages and limitations of using 4FB in laboratory experiments, as well as potential future directions. 
 

Scientific Research Applications

• Chemical Synthesis and Properties:
  • 4-Fluoro-1-butanol has been used in the synthesis of fluoronitroalcohols and their derivatives. These compounds are prepared through aqueous fluorination, which is a key process in organic synthesis (Eremenko et al., 1970).
• Analytical Applications in Biological Research:
  • In analytical chemistry, 4-Fluoro-1-butanol plays a role in the development of sensitive fluorometric methods. For instance, it has been involved in the analysis of proline in biological samples, showcasing its utility in biomedical research (Wu, 1993).
• Study of Cellular Processes:
  • Research on cellular processes, such as phospholipase D (PLD) inhibition, has utilized 4-Fluoro-1-butanol. This compound aids in understanding the role of PLD in cell spreading, chemotaxis, and membrane vesicle trafficking, offering insights into potential therapeutic applications (Su et al., 2009).
• Applications in Biofuel Research:
  • Butanol, including 4-Fluoro-1-butanol, is being explored as a potential biofuel. Studies in biotechnology and bioengineering are focused on the fermentative production of butanol, highlighting its significance in sustainable energy research (Lee et al., 2008).
• Physical Chemistry and Molecular Structure Studies:
  • The physical properties and conformational analysis of fluorine-containing alcohols, including 4-Fluoro-1-butanol, are subjects of interest. Investigations into their conformational landscape and relaxation paths provide fundamental insights into their molecular structures (Lu et al., 2020).
• Material Science and Engineering Applications:
  • In material science, the study of micelle formation in solutions involving 4-Fluoro-1-butanol can reveal important aspects of surfactant behavior, which is critical in various industrial applications (Lianos & Zana, 1980).
• Gas and Vapor Separation Technologies:
  • The compound is also relevant in the development of gas/vapor separation technologies. Metal-organic frameworks (MOFs) utilizing 4-Fluoro-1-butanol have been explored for their potential in selective adsorption and molecular sieving of gases and vapors (Xue et al., 2015).

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