374-14-1 | 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

CAS:374-14-1 | 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE,Description

Synthesis Analysis

Although there isn't a direct study focusing solely on the synthesis of 2,2,3,3,3-Pentafluoropropylamine hydrochloride, related research provides insights into methodologies that might be applicable. For instance, the synthesis of similar fluorinated compounds involves complex reactions where fluorine atoms significantly alter the chemical behavior and properties of the molecules. Techniques such as the treatment of corresponding epoxy compounds with amines under controlled conditions might be relevant (H. Plenkiewicz & W. Dmowski, 1989).

Scientific Research Applications

• Chemistry of Polyfluorocarbanions : 2H-Pentafluoropropene, a related compound, reacts with sodium methanethiolate in ether to yield specific sulphide compounds (Haszeldine, Mcallister, & Tipping, 1975).
• Hydrophobic Surfaces on Cellulose Fibers : Vapor-phase-assisted photopolymerization of 2,2,3,3,3-pentafluoropropylmethacrylate can create hydrophobic surfaces on cellulose fibers without altering their original properties (Andou et al., 2010).
• Detection of Methamphetamine Hydrochloride : Polyfluorene with NH2-terminated side chains, which include the pentafluoropropylamine group, is effective in detecting Methamphetamine Hydrochloride with a low detection limit (He et al., 2011).
• GC-MS Studies in Drug Analysis : Perfluoroacyl derivatives like pentafluoropropionylamides are utilized in gas chromatography-mass spectrometry (GC-MS) for specific side-chain identification in studies of methylenedioxymethamphetamine (Awad, Deruiter, & Clark, 2005).
• Fluorinating Agents in Organic Synthesis : Secondary amine adducts of 1,1,3,3,3-pentafluoropropene are effective fluorinating agents, substituting hydroxyl groups in alcohols with fluorine (Koroniak et al., 2006).
• Organic and Organometallic Chemistry : Tris(pentafluorophenyl)borane, a related compound, is a catalyst used for various reactions such as hydrometallation, alkylations, and aldol-type reactions (Erker, 2005).
• Isotopic Analysis in Geology : Bromine pentafluoride is employed for the quantitative liberation of oxygen from oxides and silicates for isotopic analysis, enhancing oxygen yields and reducing errors in isotopic composition (Clayton & Mayeda, 1963).
• Detection of Carbonyl-Containing Compounds : O-(2,3,4,5,6-pentafluorophenyl)methylhydroxylamine hydrochloride is a versatile reagent for determining carbonyl-containing compounds in various samples like water, air, and clothing (Cancilla & Que Hee, 1992).
• Environmental Hazards and Recovery of Solvents : Hydrochlorofluorocarbons (HCFCs), related compounds, are used as interim replacements for chlorofluorocarbons (CFCs) due to their lower environmental impact (Tsai, 2002).
• Organic Electronics and Battery Technology : Fluorinated cyclic phosphorus(III)-based compounds are used in lithium-ion batteries for high voltage applications, contributing to the formation of a cathode electrode (von Aspern et al., 2019).

Safety And Hazards

The compound is classified as Skin Corr. 1B according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). The precautionary statements include P280, P303 + P361 + P353, P304 + P340 + P310, P305 + P351 + P338, P363, and P405.

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