374-25-4 | 4-Bromo-3-chloro-3,4,4-trifluorobut-1-ene

CAS:374-25-4 | 4-Bromo-3-chloro-3,4,4-trifluorobut-1-ene ,Description

4-Bromo-3-chloro-3,4,4-trifluorobut-1-ene (BCTFB) is an organic compound with a halogenated aliphatic structure. It has a wide range of applications in scientific research, from synthesis methods to biochemical and physiological effects. This article will discuss the synthesis methods, scientific research applications, mechanism of action, biochemical and physiological effects, advantages and limitations for lab experiments, and future directions for BCTFB.
 

Scientific Research Applications

NMR Spectroscopy Studies

4-Bromo-3-chloro-3,4,4-trifluorobut-1-ene has been extensively studied through nuclear magnetic resonance (NMR) spectroscopy. Hinton and Jaques (1974) conducted a detailed investigation using 19F, 13C, and 1H NMR spectroscopy, analyzing chemical shifts and coupling constants of the compound. They explored temperature and solvent effects on these parameters, offering insights into the molecule's behavior under varying conditions (Hinton & Jaques, 1974).

Copolymerization and Synthesis

The compound plays a significant role in the copolymerization process. Guiot et al. (2005) studied the radical copolymerization of vinylidene fluoride with 4-bromo-1,1,2-trifluorobut-1-ene. This research contributed to understanding the kinetics of copolymerization and the reactivity ratios of involved compounds (Guiot et al., 2005).

Organic Molecule Synthesis

Konno et al. (2011) demonstrated the use of 4-bromo-3,3,4,4-tetrafluorobut-1-ene in the reductive coupling with various carbonyl compounds. This method provided a pathway for integrating the tetrafluoroethylene unit into organic molecules, expanding the scope of organic synthesis (Konno et al., 2011).

Cycloadducts and Cross-Coupling

Koldobskii et al. (2009) explored the formation of cycloadducts through the reaction of 4-bromo-1,1,1-trifluorobut-3-yn-2-one with conjugated dienes. This study highlighted the potential for creating novel compounds via halogen substitution in cross-coupling reactions (Koldobskii et al., 2009).

Fluorinated Molecules and Polymer Research

Research by Paleta et al. (2000) involved the synthesis of fluorinated butanolides and butenolides. They utilized a precursor similar to 4-bromo-3-chloro-3,4,4-trifluorobut-1-ene, demonstrating its relevance in creating fluorinated organic compounds with potential applications in polymer chemistry (Paleta et al., 2000).

Radical Addition and Fluorination

Gregory et al. (1971) studied the photochemical reactions involving trifluoroiodomethane and 1,1,1-trifluorobut-2-ene, a related compound. Their findings contribute to understanding the radical addition processes and fluorination in organic synthesis (Gregory et al., 1971).

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