377-38-8 | Tetrafluorosuccinic acid

CAS:377-38-8 | Tetrafluorosuccinic acid ,Description

Tetrafluorosuccinic acid, or TFSA, is an inorganic compound that is widely used in a variety of scientific research applications, such as synthesis and chromatography. It is a colorless, water-soluble solid that is highly stable and has a low vapor pressure. It is also commonly used as a reagent in organic synthesis, and its properties make it an ideal choice for a variety of laboratory experiments. 
 

Scientific Research Applications

Electron Attachment and Ionization Studies

Tetrafluorosuccinic acid has been studied for its electron affinities and ionization properties. In research conducted by Cooper and Compton (1974), electron attachment and cesium collisional ionization techniques were employed to explore the molecular electron affinities of tetrafluorosuccinic anhydride. The study found significant dissociative electron attachment producing various negative ions, indicating the compound's potential in fields such as materials science and analytical chemistry (Cooper & Compton, 1974).

Synthesis and Structural Analysis

The synthesis and x-ray structural analysis of N-substituted diamides of tetrafluorosuccinic acids have been topics of interest in the chemical synthesis realm. Fokin et al. (1989) successfully synthesized new N-substituted diamides of tetrafluorosuccinic acids and elucidated the molecular and crystal structure of one such compound, contributing to the understanding of its chemical properties and potential applications in material science and organic synthesis (Fokin et al., 1989).

Hybrid Inorganic-Organic Materials

Tetrafluorosuccinic acid has been utilized in the ionothermal synthesis of hybrid inorganic-organic frameworks, demonstrating the versatility of this compound in materials science. Hulvey et al. (2009) synthesized new phases containing perfluorinated dicarboxylate ligands, showing the potential of tetrafluorosuccinic acid in creating novel materials with unique properties (Hulvey et al., 2009).

Fluorination Reagents and Applications

The derivatives and reactivity of tetrafluorosuccinic acid-related compounds have significant implications in fluorination chemistry. Zhang et al. (2014) discussed the synthesis, reactivity, and applications of various fluorosulfonyldifluoroacetic acid derivatives, highlighting the role of tetrafluorosuccinic acid derivatives in the design of drug candidates and synthesis of functional materials (Zhang et al., 2014).

Catalytic Dehydrogenation

In the field of catalysis, tetrafluorosuccinic acid has been employed in the formation of dinuclear ruthenium complexes that catalyze the acceptorless dehydrogenation of secondary alcohols. Buijtenen et al. (2006) demonstrated the synthesis and catalytic activity of such complexes, providing insights into the potential applications of tetrafluorosuccinic acid in catalytic processes (Buijtenen et al., 2006).

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