378-75-6 | Methyl pentafluoropropionate

CAS:378-75-6 | Methyl pentafluoropropionate ,Description

Methyl pentafluoropropionate (MPFP) is an organofluorine compound that has been used in a variety of scientific research applications. It is a colorless, volatile liquid with a melting point of -45°C and a boiling point of -11.5°C. MPFP is an important intermediate in the synthesis of a variety of organic compounds, and it has been used in the synthesis of pharmaceuticals, agrochemicals, and other industrial products. In addition to its use as a synthetic intermediate, MPFP has also been used in a variety of scientific research applications, such as in the study of biochemical and physiological effects. 
 

Scientific Research Applications

Preparation of Tetrafluoroethylene

Methyl pentafluoropropionate has been utilized in the preparation of tetrafluoroethylene (TFE) via pyrolysis. This process involves the decomposition of pentafluoropropionate salts, derived from pentafluoropropionic acid, under dynamic vacuum. This method yields high-purity TFE, a compound with significant industrial applications, especially in polymer production (Hercules et al., 2017).

Electron Spin Resonance Analysis

Research has been conducted on the electron spin resonance of γ-irradiated single crystals of compounds related to methyl pentafluoropropionate, such as pentafluoropropionamide. These studies have helped in understanding the formation of stable free radicals and their interactions at the molecular level, which is crucial in fields like radiation chemistry and material science (Lontz, 1966) .

Analytical Chemistry Applications

In analytical chemistry, derivatives of methyl pentafluoropropionate have been used in gas chromatographic and mass spectrometric analyses. For instance, it has been applied in studying the metabolism of anesthetic agents, highlighting its role as an internal standard and a reactant in complex chemical analyses (Gruenke & Waskell, 1988).

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