382-31-0 | 2,2,3,4,4,4-Hexafluorobutan-1-ol

CAS:382-31-0 | 2,2,3,4,4,4-Hexafluorobutan-1-ol ,Description

2,2,3,4,4,4-Hexafluorobutan-1-ol (HFB) is a chemical compound with a wide range of applications in both industry and research. HFB is a colorless, volatile liquid with a melting point of -91.3°C and a boiling point of -55.8°C. It is a fluorinated hydrocarbon and a member of the hexafluorobutane family. HFB is used as a reagent in organic synthesis, as a solvent in the production of pharmaceuticals, and as a starting material in the manufacture of fluorinated polymers. It has also been studied for its potential use in the treatment of neurological disorders and as a fuel additive.
 

Scientific Research Applications

Diffusion and Solubility Studies

Research has been conducted on the diffusion coefficients of various fluorinated surfactants in water, including compounds closely related to 2,2,3,4,4,4-Hexafluorobutan-1-ol. This includes studies on 2,2,3,3,3-pentafluoropropan-1-ol and 2,2,3,3,4,4,4-heptafluorobutan-1-ol, examining their behavior in water through both experimental and computer simulation methods. These studies provide insights into the solubility and diffusion properties of these fluorinated compounds in aqueous solutions (Pereira et al., 2014).

Radical Cation Stabilization

1,1,1,3,3,3-Hexafluoropropan-2-ol (HFP), a compound with similar fluorination to 2,2,3,4,4,4-Hexafluorobutan-1-ol, demonstrates unique solvent properties, making it ideal for stabilizing radical cations. This application is particularly relevant in EPR spectroscopy and the study of radical cations in electrophilic aromatic substitution and photochemistry (Eberson et al., 1997).

Chemical Synthesis Applications

The compound 2,2,3,4,4,4-Hexafluorobutan-1-ol and related chemicals have been used in various chemical syntheses. For example, a study on the synthesis of 1,1,1,4,4,4-hexafluorobutane from succinonitrile demonstrates the application of hexafluorobutanes in organic synthesis (Baker et al., 1999).

NMR Spectroscopy

Fluorinated compounds, including 1,1,1,4,4,4-hexafluorobutane, have been extensively studied using nuclear magnetic resonance (NMR) spectroscopy. This research has provided detailed insights into the chemical structure and behavior of these compounds in solution (Abraham & Loftus, 1973).

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