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2-Fluoroethyl 4-methylbenzenesulfonate (FEMBS) is an organosulfonate used in organic synthesis as a reagent for the synthesis of a variety of organic compounds. It is a versatile reagent and has been used in a wide variety of laboratory experiments and research. FEMBS is a colorless, odorless, and water-soluble compoun...
2-Fluoroethyl 4-methylbenzenesulfonate (FEMBS) is an organosulfonate used in organic synthesis as a reagent for the synthesis of a variety of organic compounds. It is a versatile reagent and has been used in a wide variety of laboratory experiments and research. FEMBS is a colorless, odorless, and water-soluble compound that is relatively stable and non-toxic. It is a useful reagent for the preparation of a variety of organic compounds such as amines, heterocycles, and carboxylic acids.
2-Fluoroethyl 4-methylbenzenesulfonate is utilized in the high-yield, automated radiosynthesis of [18F]FDDNP, a positron emission tomography (PET) imaging probe for Alzheimer’s and other neurodegenerative diseases. This synthesis, including the characterization of non-radioactive FDDNP, is significant for advancing PET imaging technologies (Liu et al., 2006).
The 4-methylbenzenesulfonate anion, a component of 2-Fluoroethyl 4-methylbenzenesulfonate, has been studied using ab initio quantum chemical methods and IR and Raman spectra. This research is crucial for understanding the molecular structure and vibrational modes of 4-methylbenzenesulfonate salts (Ristova et al., 1999).
In solid phase radiofluorination, 2-Fluoroethyl 4-methylbenzenesulfonate is instrumental in achieving high radiochemical yields. This research is significant for developing efficient methods in radiochemistry and PET tracer production (Mathiessen et al., 2015).
2-Fluoroethyl 4-methylbenzenesulfonate, also known as 2-fluoroethyl tosylate, is widely used for labeling radioligands in PET imaging. Its role in synthesizing various radioligands exemplifies its importance in medical imaging and diagnostic procedures (Jarkas et al., 2013).
The compound is referenced in studies on organic crystals, such as 4-methylbenzenesulfonate, for their nonlinear optical properties and their potential in optical-to-THz conversion, highlighting its relevance in materials science and photonics (Lee et al., 2018) .
4-Methylbenzenesulfonate derivatives, like 4-fluorobenzenesulfonate, have been used to activate hydroxyl groups of polymeric carriers for the covalent attachment of biologicals to solid supports. This research is significant in the field of bioconjugate chemistry (Chang et al., 1992).
Product Name : | 2-Fluoroethyl 4-methylbenzenesulfonate | ||
CAS No. : | 383-50-6 | Molecular Weight : | 218.25 |
MDL No. : | MFCD01658061 | Purity/ Specification : | |
Molecular Formula : | C9H11FO3S | Storage : | Inert atmosphere,Room Temperature |
Boiling Point : | - |
GHS Pictogram : | |||
Signal Word : | Warning | Precautionary Statements : | P261-P305+P351+P338 |
UN# : | N/A | Class : | N/A |
Hazard Statements : | H302-H315-H319-H335 | Packing Group : | N/A |