406-95-1 | 2,2,2-Trifluoroethyl acetate

CAS:406-95-1 | 2,2,2-Trifluoroethyl acetate ,Description

2,2,2-Trifluoroethyl acetate (TFEA) is a volatile organic compound (VOC) used as a solvent in various industrial processes. It is a colorless liquid with a sweet odor, and is soluble in water and most organic solvents. It is a common ingredient in paints, coatings, and adhesives, and is also used as a solvent in the production of pharmaceuticals. TFEA has also been used as a reagent in the synthesis of various compounds, as well as in the preparation of various catalysts and catalytic systems.
 

Scientific Research Applications

Electrochemical Capacitors

2,2,2-Trifluoroethyl acetate and its analogs have been studied for their potential in enhancing the stability of electrochemical capacitors at higher voltages. Research conducted by Krause et al. (2021) demonstrated that fluorinated additives, including 2,2,2-trifluoroethyl analogs, could improve capacitor stability and retention of capacitance at voltages between 3.5 and 4.0 V. This suggests new strategies for increasing the operating limits of supercapacitors, thus enhancing their energy storage and compatibility with lithium-ion battery cells in hybrid configurations (Krause et al., 2021).

Mass Spectrometry Analysis

The compound has also been utilized in mass spectrometry studies. Fujishige et al. (1998) investigated the unimolecular decompositions of metastable ions produced from 2,2,2-trifluoroethyl acetate under electron impact. Their work contributes to the understanding of the behavior of this compound in mass-analyzed ion kinetic energy spectrometry and aids in the interpretation of mass spectral data (Fujishige et al., 1998).

Synthesis of Onium Salts

In the field of organic chemistry, Umemoto and Gotoh (1991) reported the synthesis of various 2,2,2-trifluoroethyl onium triflates using (2,2,2-trifluoroethyl)phenyliodonium triflate. This research illustrates the potential of 2,2,2-trifluoroethyl acetate derivatives in synthesizing complex organic salts, expanding the toolbox available for organic synthesis and chemical reactions (Umemoto & Gotoh, 1991).

Electrophilic Fluorination

Zhao and Hu (2012) explored the use of 2,2,2-trifluoroethyl acetate derivatives in the electrophilic fluorination of organoboronic acids and esters. This study sheds light on novel methods for introducing fluorinated moieties into organic molecules, which is significant in drug design and medicinal chemistry (Zhao & Hu, 2012).

Lithium-Ion Batteries

Doi et al. (2021) investigated 2,2,2-trifluoroethyl acetate-based electrolyte solutions for lithium-ion batteries. They found that these solutions offered improved charge/discharge performance for certain electrodes, highlighting the role of 2,2,2-trifluoroethyl acetate in developing more efficient energy storage solutions (Doi et al., 2021).

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