422-05-9 | 2,2,3,3,3-Pentafluoro-1-propanol

CAS:422-05-9 | 2,2,3,3,3-Pentafluoro-1-propanol ,Description

2,2,3,3,3-Pentafluoro-1-propanol (PFP) is an organic compound that has a wide range of applications in the pharmaceutical and chemical industries. It is a colorless, volatile liquid with a distinctive odor and is a member of the class of compounds known as fluorinated alcohols. PFP has been used as a solvent in organic synthesis, as a reagent in organic synthesis, and as a surfactant in a variety of industrial applications. It is also used as an intermediate in the production of pharmaceuticals, such as antifungal agents, and as an additive in gasoline.
 

Scientific Research Applications

Conformational Analysis and Spectroscopy

• Solvent-Dependent Conformational Stability: The conformational stability of 2,2,3,3,3-pentafluoro-1-propanol varies with the solvent used. A study by Badawi and Förner (2008) using DFT-B3LYP/6-311+G** and ab initio MP2/6-311+G** calculations revealed distinct minima corresponding to different conformers, indicating solvent-dependent conformational changes (Badawi & Förner, 2008).
• Vibrational Spectra Analysis: The same study also performed a detailed analysis of the vibrational spectra of 2,2,3,3,3-pentafluoro-1-propanol, contributing to a better understanding of its molecular structure and behavior in different states (Badawi & Förner, 2008).

Structural Diversity and Chemical Interactions

• Rotational Spectra and Structural Diversity: Wu et al. (2022) explored the rotational spectra of 2,2,3,3,3-pentafluoro-1-propanol using advanced spectroscopic techniques. This study revealed a high degree of structural diversity and complex chemical interactions within its molecular framework, highlighting its potential in various chemical applications (Wu et al., 2022).

Environmental Applications

• Adsorption Mechanisms for Environmental Recovery: Kawasaki et al. (1997) investigated the adsorption mechanisms of 2,2,3,3,3-pentafluoro-1-propanol on activated carbons. This research is crucial for environmental recovery and recycling processes, especially in reducing the environmental impact of organic solvents (Kawasaki et al., 1997).
• Use in Heat Pumps and Rankine Cycle Systems: A study by 遠上 and 野口 (1985) explored the thermodynamic properties and thermal stability of 2,2,3,3,3-pentafluoro-1-propanol when used in Rankine cycle systems and heat pumps, indicating its utility in energy-efficient systems (遠上 & 野口, 1985) .

Chemical Synthesis and Catalysis

• Synthesis of Fluorinated Compounds: Jiménez et al. (2005) demonstrated a new method for synthesizing long-chain 2,2-difluoro-3-hydroxyacids using 2,2,3,3,3-pentafluoro-1-propanol. This highlights its role in the synthesis of complex fluorinated compounds, which are valuable in various industrial applications (Jiménez et al., 2005) .

Electrochemical Applications

• Electrocatalytic Reactions: Wang et al. (2014) utilized 2,2,3,3-tetrafluoro-1-propanol in an electrocatalytic reactor for producing sodium 2,2,3,3-tetrafluoropropionate. This study showcases the potential of 2,2,3,3,3-pentafluoro-1-propanol in electrochemical applications and its role in producing high-value chemicals (Wang et al., 2014).

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