431-47-0 | Methyl trifluoroacetate

CAS:431-47-0 | Methyl trifluoroacetate ,Description

Methyl trifluoroacetate (MTF) is a colorless, volatile, non-flammable, and water-soluble liquid with a wide range of applications in various industries. It is a common reagent in organic synthesis, and has been used in the production of pharmaceuticals, agrochemicals, and other high-value products. In addition, MTF is also used in the production of perfumes, fragrances, and other consumer products. MTF has also been studied for its potential applications in biomedical research and biotechnology. 
 

Scientific Research Applications

Gas Chromatography

Maiorino, Gandolfi, and Sipes (1980) developed a gas-chromatographic method using MTFA for the quantitative determination of bromide and trifluoroacetic acid in biological fluids. This method is valuable for studying urine and blood metabolite levels, providing insights into the metabolism of halothane, an anesthetic agent (Maiorino, Gandolfi, & Sipes, 1980).

Lithium-Ion Battery Electrolytes

Lu et al. (2013) investigated the effects of carbon-chain length in trifluoroacetate solvents, including MTFA, for lithium-ion battery electrolytes at low temperatures. MTFA was found to be a suitable co-solvent, affecting the mobility of solvated lithium ions (Lu et al., 2013).

Nucleophilic Trifluoromethylation

Langlois and Roques (2007) demonstrated the utility of MTFA as a trifluoromethylating agent in the substitution of aromatic iodides and bromides. This application is significant in organic synthesis, particularly in the production of aromatic compounds (Langlois & Roques, 2007).

Organic Synthesis

Yu, Xu, and Qing (2016) explored MTFA in photoredox catalysis for organic synthesis, demonstrating its role in the production of carbomethoxydifluoromethylated products under visible light conditions (Yu, Xu, & Qing, 2016).

Environmental Monitoring

MTFA's role in environmental monitoring is highlighted by Wujcik, Cahill, and Seiber (1998) in their development of a method for analyzing trifluoroacetic acid in environmental waters. They utilized MTFA for quantitative recovery and analysis of trifluoroacetic acid at low ppt levels in aqueous samples (Wujcik, Cahill, & Seiber, 1998).

Biodiesel Production

Miao, Li, and Yao (2009) reported the use of trifluoroacetic acid in the transesterification process for biodiesel production, indicating its potential as an effective catalyst in this field (Miao, Li, & Yao, 2009).

Methane Oxidation

Yuan, Wang, and Wang (2011) explored the catalysis of methane to methanol derivative using MTFA, which is a significant development in the field of industrial chemistry (Yuan, Wang, & Wang, 2011).

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